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NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2V617F-positive myeloproliferative neoplasm cells.
Fenerich BA, Fernandes JC, Rodrigues Alves APN, Coelho-Silva JL, Scopim-Ribeiro R, Scheucher PS, Eide CA, Tognon CE, Druker BJ, Rego EM, Machado-Neto JA, Traina F. Fenerich BA, et al. Among authors: rodrigues alves apn. Signal Transduct Target Ther. 2020 Jan 24;5(1):5. doi: 10.1038/s41392-019-0102-5. Signal Transduct Target Ther. 2020. PMID: 32296029 Free PMC article.
Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis.
Machado-Neto JA, Fenerich BA, Rodrigues Alves APN, Fernandes JC, Scopim-Ribeiro R, Coelho-Silva JL, Traina F. Machado-Neto JA, et al. Among authors: rodrigues alves apn. Clinics (Sao Paulo). 2018 Oct 11;73(suppl 1):e566s. doi: 10.6061/clinics/2018/e566s. Clinics (Sao Paulo). 2018. PMID: 30328953 Free PMC article. Review.
Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms.
Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F. Machado-Neto JA, et al. Among authors: rodrigues alves apn. Cell Death Dis. 2018 Feb 22;9(3):311. doi: 10.1038/s41419-017-0256-4. Cell Death Dis. 2018. PMID: 29472557 Free PMC article.
Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells.
Machado-Neto JA, Rodrigues Alves APN, Fernandes JC, Coelho-Silva JL, Scopim-Ribeiro R, Fenerich BA, da Silva FB, Scheucher PS, Simões BP, Rego EM, Traina F. Machado-Neto JA, et al. Among authors: rodrigues alves apn. Heliyon. 2017 Sep 28;3(9):e00405. doi: 10.1016/j.heliyon.2017.e00405. eCollection 2017 Sep. Heliyon. 2017. PMID: 29034341 Free PMC article.