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The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2).
Cancer Lett. 2021 Oct 10;518:72-81. doi: 10.1016/j.canlet.2021.06.012. Epub 2021 Jun 16.
Cancer Lett. 2021.
PMID: 34144098
The tumor-associated Tn antigen fosters lung metastasis and recruitment of regulatory T cells in triple negative breast cancer.
Festari MF, da Costa V, Rodríguez-Zraquia SA, Costa M, Landeira M, Lores P, Solari-Saquieres P, Kramer MG, Freire T.
Festari MF, et al. Among authors: rodriguez zraquia sa.
Glycobiology. 2022 Apr 21;32(5):366-379. doi: 10.1093/glycob/cwab123.
Glycobiology. 2022.
PMID: 34939098
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Lung Tumor Cells with Different Tn Antigen Expression Present Distinctive Immunomodulatory Properties.
Costa VD, Mariño KV, Rodríguez-Zraquia SA, Festari MF, Lores P, Costa M, Landeira M, Rabinovich GA, van Vliet SJ, Freire T.
Costa VD, et al. Among authors: rodriguez zraquia sa.
Int J Mol Sci. 2022 Oct 10;23(19):12047. doi: 10.3390/ijms231912047.
Int J Mol Sci. 2022.
PMID: 36233358
Free PMC article.
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Macrophage Gal/GalNAc lectin 2 (MGL2)+ peritoneal antigen presenting cells during Fasciola hepatica infection are essential for regulatory T cell induction.
Costa M, da Costa V, Lores P, Landeira M, Rodríguez-Zraquia SA, Festari MF, Freire T.
Costa M, et al. Among authors: rodriguez zraquia sa.
Sci Rep. 2022 Oct 21;12(1):17661. doi: 10.1038/s41598-022-21520-w.
Sci Rep. 2022.
PMID: 36271272
Free PMC article.
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Eosinophils Control Liver Damage by Modulating Immune Responses Against Fasciola hepatica.
Frigerio S, da Costa V, Costa M, Festari MF, Landeira M, Rodríguez-Zraquia SA, Härtel S, Toledo J, Freire T.
Frigerio S, et al. Among authors: rodriguez zraquia sa.
Front Immunol. 2020 Sep 18;11:579801. doi: 10.3389/fimmu.2020.579801. eCollection 2020.
Front Immunol. 2020.
PMID: 33042162
Free PMC article.
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Heme-Oxygenase-1 Attenuates Oxidative Functions of Antigen Presenting Cells and Promotes Regulatory T Cell Differentiation during Fasciola hepatica Infection.
Costa M, da Costa V, Frigerio S, Festari MF, Landeira M, Rodríguez-Zraquia SA, Lores P, Carasi P, Freire T.
Costa M, et al. Among authors: rodriguez zraquia sa.
Antioxidants (Basel). 2021 Dec 3;10(12):1938. doi: 10.3390/antiox10121938.
Antioxidants (Basel). 2021.
PMID: 34943041
Free PMC article.
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Liver function markers and haematological dynamics during acute and chronic phases of experimental Fasciola hepatica infection in cattle treated with triclabendazole.
Costa M, Saravia A, Ubios D, Lores P, da Costa V, Festari MF, Landeira M, Rodríguez-Zraquia SA, Banchero G, Freire T.
Costa M, et al. Among authors: rodriguez zraquia sa.
Exp Parasitol. 2022 Jul;238:108285. doi: 10.1016/j.exppara.2022.108285. Epub 2022 May 30.
Exp Parasitol. 2022.
PMID: 35654132
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