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Page 1
Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S. Marsal-Beltran A, et al. Among authors: rodriguez pena mm. Metabolism. 2023 Aug;145:155630. doi: 10.1016/j.metabol.2023.155630. Epub 2023 Jun 13. Metabolism. 2023. PMID: 37315889 Free article.
Changes in glucagon-like peptide 1 and 2 levels in people with obesity after a diet-induced weight-loss intervention are related to a specific microbiota signature: A prospective cohort study.
Rodríguez-Peña MM, Astiarraga B, Seco J, Ceperuelo-Mallafré V, Caballé A, Pérez-Brocal V, Attolini CS, Moya A, Llauradó G, Megía A, Pellitero S, Vilarrasa N, Fernández-Veledo S, Vendrell J. Rodríguez-Peña MM, et al. Clin Transl Med. 2021 Nov;11(11):e575. doi: 10.1002/ctm2.575. Clin Transl Med. 2021. PMID: 34841718 Free PMC article. No abstract available.
Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate.
Huber-Ruano I, Calvo E, Mayneris-Perxachs J, Rodríguez-Peña MM, Ceperuelo-Mallafré V, Cedó L, Núñez-Roa C, Miro-Blanch J, Arnoriaga-Rodríguez M, Balvay A, Maudet C, García-Roves P, Yanes O, Rabot S, Grimaud GM, De Prisco A, Amoruso A, Fernández-Real JM, Vendrell J, Fernández-Veledo S. Huber-Ruano I, et al. Among authors: rodriguez pena mm. Microbiome. 2022 Aug 25;10(1):135. doi: 10.1186/s40168-022-01306-y. Microbiome. 2022. PMID: 36002880 Free PMC article.
SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression.
Villanueva-Carmona T, Cedó L, Madeira A, Ceperuelo-Mallafré V, Rodríguez-Peña MM, Núñez-Roa C, Maymó-Masip E, Repollés-de-Dalmau M, Badia J, Keiran N, Mirasierra M, Pimenta-Lopes C, Sabadell-Basallote J, Bosch R, Caubet L, Escolà-Gil JC, Fernández-Real JM, Vilarrasa N, Ventura F, Vallejo M, Vendrell J, Fernández-Veledo S. Villanueva-Carmona T, et al. Among authors: rodriguez pena mm. Cell Metab. 2023 Apr 4;35(4):601-619.e10. doi: 10.1016/j.cmet.2023.03.004. Epub 2023 Mar 27. Cell Metab. 2023. PMID: 36977414 Free article.
A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass.
Hernández-Montoliu L, Rodríguez-Peña MM, Puig R, Astiarraga B, Guerrero-Pérez F, Virgili N, López-Urdiales R, Osorio J, Monseny R, Lazzara C, Sobrino L, Pérez-Maraver M, Pérez-Prieto M, Pellitero S, Fernández-Veledo S, Vendrell J, Vilarrasa N. Hernández-Montoliu L, et al. Among authors: rodriguez pena mm. Front Endocrinol (Lausanne). 2023 Oct 17;14:1181744. doi: 10.3389/fendo.2023.1181744. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37916149 Free PMC article. Clinical Trial.
SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes.
Sabadell-Basallote J, Astiarraga B, Castaño C, Ejarque M, Repollés-de-Dalmau M, Quesada I, Blanco J, Nuñez-Roa C, Rodríguez-Peña MM, Martínez L, De Jesus DF, Marroqui L, Bosch R, Montanya E, Sureda FX, Tura A, Mari A, Kulkarni RN, Vendrell J, Fernández-Veledo S. Sabadell-Basallote J, et al. Among authors: rodriguez pena mm. J Clin Invest. 2024 May 7:e173214. doi: 10.1172/JCI173214. Online ahead of print. J Clin Invest. 2024. PMID: 38713514 Free article.