Rodríguez-Franco MI - Search Results

1

Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders.

Espadinha M, Viejo L, Lopes RMRM, Herrera-Arozamena C, Molins E, Dos Santos DJVA, Gonçalves L, Rodríguez-Franco MI, Ríos CL, Santos MMM. Espadinha M, et al. Eur J Med Chem. 2020 May 15;194:112242. doi: 10.1016/j.ejmech.2020.112242. Epub 2020 Mar 23. Eur J Med Chem. 2020. PMID: 32248004

2

Synthesis and muscarinic activities of O-[(benzyl- or benzoyl-pyrazolyl)propynyl]-oximes of N-methylpiperidinone, 3-tropinone, and 3-quinuclidinone.

Rodríguez-Franco MI, Dorronsoro I, Castro A, Martínez A, Badía A, Baños JE. Rodríguez-Franco MI, et al. Bioorg Med Chem. 2003 May 15;11(10):2263-8. doi: 10.1016/s0968-0896(03)00111-1. Bioorg Med Chem. 2003. PMID: 12713836

3

Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase.

Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Castro A, Martínez A. Rodríguez-Franco MI, et al. Bioorg Med Chem. 2005 Dec 15;13(24):6795-802. doi: 10.1016/j.bmc.2005.07.019. Epub 2005 Sep 23. Bioorg Med Chem. 2005. PMID: 16183292

4

Novel tacrine-melatonin hybrids as dual-acting drugs for Alzheimer disease, with improved acetylcholinesterase inhibitory and antioxidant properties.

Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Hernández-Ledesma B, Bartolomé B. Rodríguez-Franco MI, et al. J Med Chem. 2006 Jan 26;49(2):459-62. doi: 10.1021/jm050746d. J Med Chem. 2006. PMID: 16420031

5

Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.

Arce MP, Rodríguez-Franco MI, González-Muñoz GC, Pérez C, López B, Villarroya M, López MG, García AG, Conde S. Arce MP, et al. J Med Chem. 2009 Nov 26;52(22):7249-57. doi: 10.1021/jm900628z. J Med Chem. 2009. PMID: 19856923

6

Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.

Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. J Med Chem. 2010 Jul 8;53(13):4927-37. doi: 10.1021/jm100329q. J Med Chem. 2010. PMID: 20545360

7

Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases.

González-Muñoz GC, Arce MP, López B, Pérez C, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Eur J Med Chem. 2010 Dec;45(12):6152-8. doi: 10.1016/j.ejmech.2010.09.039. Eur J Med Chem. 2010. PMID: 20926162

8

N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.

González-Muñoz GC, Arce MP, López B, Pérez C, Romero A, del Barrio L, Martín-de-Saavedra MD, Egea J, León R, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Eur J Med Chem. 2011 Jun;46(6):2224-35. doi: 10.1016/j.ejmech.2011.03.003. Epub 2011 Mar 21. Eur J Med Chem. 2011. PMID: 21420206

9

Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.

Chioua M, Sucunza D, Soriano E, Hadjipavlou-Litina D, Alcázar A, Ayuso I, Oset-Gasque MJ, González MP, Monjas L, Rodríguez-Franco MI, Marco-Contelles J, Samadi A. Chioua M, et al. J Med Chem. 2012 Jan 12;55(1):153-68. doi: 10.1021/jm201105a. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22126405

10

Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases.

Galdeano C, Viayna E, Sola I, Formosa X, Camps P, Badia A, Clos MV, Relat J, Ratia M, Bartolini M, Mancini F, Andrisano V, Salmona M, Minguillón C, González-Muñoz GC, Rodríguez-Franco MI, Bidon-Chanal A, Luque FJ, Muñoz-Torrero D. Galdeano C, et al. J Med Chem. 2012 Jan 26;55(2):661-9. doi: 10.1021/jm200840c. Epub 2012 Jan 10. J Med Chem. 2012. PMID: 22185619

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