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Emerging agents for the treatment of Chagas disease: what is in the preclinical and clinical development pipeline?
Martínez-Peinado N, Cortes-Serra N, Losada-Galvan I, Alonso-Vega C, Urbina JA, Rodríguez A, VandeBerg JL, Pinazo MJ, Gascon J, Alonso-Padilla J. Martínez-Peinado N, et al. Among authors: rodriguez a. Expert Opin Investig Drugs. 2020 Sep;29(9):947-959. doi: 10.1080/13543784.2020.1793955. Epub 2020 Jul 19. Expert Opin Investig Drugs. 2020. PMID: 32635780 Review.
High throughput screening for anti-Trypanosoma cruzi drug discovery.
Alonso-Padilla J, Rodríguez A. Alonso-Padilla J, et al. Among authors: rodriguez a. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3259. doi: 10.1371/journal.pntd.0003259. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25474364 Free PMC article. Review.
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.
Peña I, Pilar Manzano M, Cantizani J, Kessler A, Alonso-Padilla J, Bardera AI, Alvarez E, Colmenarejo G, Cotillo I, Roquero I, de Dios-Anton F, Barroso V, Rodriguez A, Gray DW, Navarro M, Kumar V, Sherstnev A, Drewry DH, Brown JR, Fiandor JM, Julio Martin J. Peña I, et al. Among authors: rodriguez a. Sci Rep. 2015 Mar 5;5:8771. doi: 10.1038/srep08771. Sci Rep. 2015. PMID: 25740547 Free PMC article.
Anti-Trypanosoma cruzi Activity of Metabolism Modifier Compounds.
Martinez-Peinado N, Martori C, Cortes-Serra N, Sherman J, Rodriguez A, Gascon J, Alberola J, Pinazo MJ, Rodriguez-Cortes A, Alonso-Padilla J. Martinez-Peinado N, et al. Among authors: rodriguez a, rodriguez cortes a. Int J Mol Sci. 2021 Jan 12;22(2):688. doi: 10.3390/ijms22020688. Int J Mol Sci. 2021. PMID: 33445756 Free PMC article.
Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease.
Harrison JR, Sarkar S, Hampton S, Riley J, Stojanovski L, Sahlberg C, Appelqvist P, Erath J, Mathan V, Rodriguez A, Kaiser M, Pacanowska DG, Read KD, Johansson NG, Gilbert IH. Harrison JR, et al. Among authors: rodriguez a. J Med Chem. 2020 Mar 26;63(6):3066-3089. doi: 10.1021/acs.jmedchem.9b01852. Epub 2020 Mar 5. J Med Chem. 2020. PMID: 32134269
7,876 results