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Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin.
Jansen PA, Rodijk-Olthuis D, Hollox EJ, Kamsteeg M, Tjabringa GS, de Jongh GJ, van Vlijmen-Willems IM, Bergboer JG, van Rossum MM, de Jong EM, den Heijer M, Evers AW, Bergers M, Armour JA, Zeeuwen PL, Schalkwijk J. Jansen PA, et al. PLoS One. 2009;4(3):e4725. doi: 10.1371/journal.pone.0004725. Epub 2009 Mar 6. PLoS One. 2009. PMID: 19266104 Free PMC article.
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