Rochet JC - Search Results

1

Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein.

Landeck N, Strathearn KE, Ysselstein D, Buck K, Dutta S, Banerjee S, Lv Z, Hulleman JD, Hindupur J, Lin LK, Padalkar S, Stanciu LA, Lyubchenko YL, Kirik D, Rochet JC. Landeck N, et al. Among authors: rochet jc. Mol Neurodegener. 2020 Sep 8;15(1):49. doi: 10.1186/s13024-020-00380-w. Mol Neurodegener. 2020. PMID: 32900375 Free PMC article.

2

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.

Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, Labaer J, Rochet JC, Bonini NM, Lindquist S. Cooper AA, et al. Among authors: rochet jc. Science. 2006 Jul 21;313(5785):324-8. doi: 10.1126/science.1129462. Epub 2006 Jun 22. Science. 2006. PMID: 16794039 Free PMC article.

3

Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation.

Outeiro TF, Klucken J, Strathearn KE, Liu F, Nguyen P, Rochet JC, Hyman BT, McLean PJ. Outeiro TF, et al. Among authors: rochet jc. Biochem Biophys Res Commun. 2006 Dec 22;351(3):631-8. doi: 10.1016/j.bbrc.2006.10.085. Epub 2006 Oct 26. Biochem Biophys Res Commun. 2006. PMID: 17081499 Free PMC article.

4

Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease.

Hulleman JD, Mirzaei H, Guigard E, Taylor KL, Ray SS, Kay CM, Regnier FE, Rochet JC. Hulleman JD, et al. Among authors: rochet jc. Biochemistry. 2007 May 15;46(19):5776-89. doi: 10.1021/bi7001778. Epub 2007 Apr 24. Biochemistry. 2007. PMID: 17451229

5

Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.

Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Outeiro TF, et al. Among authors: rochet jc. Science. 2007 Jul 27;317(5837):516-9. doi: 10.1126/science.1143780. Epub 2007 Jun 21. Science. 2007. PMID: 17588900

6

Helical alpha-synuclein forms highly conductive ion channels.

Zakharov SD, Hulleman JD, Dutseva EA, Antonenko YN, Rochet JC, Cramer WA. Zakharov SD, et al. Among authors: rochet jc. Biochemistry. 2007 Dec 18;46(50):14369-79. doi: 10.1021/bi701275p. Epub 2007 Nov 22. Biochemistry. 2007. PMID: 18031063

7

The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis.

Gitler AD, Bevis BJ, Shorter J, Strathearn KE, Hamamichi S, Su LJ, Caldwell KA, Caldwell GA, Rochet JC, McCaffery JM, Barlowe C, Lindquist S. Gitler AD, et al. Among authors: rochet jc. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):145-50. doi: 10.1073/pnas.0710685105. Epub 2007 Dec 27. Proc Natl Acad Sci U S A. 2008. PMID: 18162536 Free PMC article.

8

Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease.

Liu F, Nguyen JL, Hulleman JD, Li L, Rochet JC. Liu F, et al. Among authors: rochet jc. J Neurochem. 2008 Jun 1;105(6):2435-53. doi: 10.1111/j.1471-4159.2008.05333.x. J Neurochem. 2008. PMID: 18331584 Free article.

9

Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults.

Liu F, Hindupur J, Nguyen JL, Ruf KJ, Zhu J, Schieler JL, Bonham CC, Wood KV, Davisson VJ, Rochet JC. Liu F, et al. Among authors: rochet jc. Free Radic Biol Med. 2008 Aug 1;45(3):242-55. doi: 10.1016/j.freeradbiomed.2008.03.022. Epub 2008 Apr 11. Free Radic Biol Med. 2008. PMID: 18456002 Free PMC article.

10

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity.

Gitler AD, Chesi A, Geddie ML, Strathearn KE, Hamamichi S, Hill KJ, Caldwell KA, Caldwell GA, Cooper AA, Rochet JC, Lindquist S. Gitler AD, et al. Among authors: rochet jc. Nat Genet. 2009 Mar;41(3):308-15. doi: 10.1038/ng.300. Epub 2009 Feb 1. Nat Genet. 2009. PMID: 19182805 Free PMC article.

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