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Regioselective synthesis, biological evaluation, and molecular docking of dihydropyrimidin-4-ols as acetylcholinesterase inhibitors.
da Silva AMPW, da Silva FM, Nogara PA, Dutra EJM, Serres JDS, Saraiva RA, Piccoli BC, Oliveira CS, Schetinger MRC, Morsch VMM, Rocha JBT, Bonacorso HG, Martins MAP, Zanatta N. da Silva AMPW, et al. Among authors: rocha jbt. Chem Biol Drug Des. 2017 Dec;90(6):1161-1172. doi: 10.1111/cbdd.13036. Epub 2017 Jul 6. Chem Biol Drug Des. 2017. PMID: 28581643
Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity.
Bianchini MC, Gularte COA, Nogara PA, Krum BN, Gayer MC, Bridi JC, Roos DH, Roehrs R, Fachinetto R, Pinton S, Ávila DS, Hirth F, Rocha JBT, Puntel RL. Bianchini MC, et al. Among authors: rocha jbt. Metallomics. 2019 Feb 20;11(2):362-374. doi: 10.1039/c8mt00268a. Metallomics. 2019. PMID: 30516209
Methylmercury's chemistry: From the environment to the mammalian brain.
Nogara PA, Oliveira CS, Schmitz GL, Piquini PC, Farina M, Aschner M, Rocha JBT. Nogara PA, et al. Among authors: rocha jbt. Biochim Biophys Acta Gen Subj. 2019 Dec;1863(12):129284. doi: 10.1016/j.bbagen.2019.01.006. Epub 2019 Jan 17. Biochim Biophys Acta Gen Subj. 2019. PMID: 30659885 Free article. Review.
Synthesis and biological evaluation of new antioxidant and antiproliferative chalcogenobiotin derivatives for bladder carcinoma treatment.
Leitemberger A, Sonego MS, Garcia FD, Dos Santos ACF, Piccoli BC, da Silva FD, Oliveira CS, Seixas FK, Dornelles L, Rocha JBT, Nogara PA, Schachtschneider KM, Collares T, Rodrigues OED. Leitemberger A, et al. Among authors: rocha jbt. Bioorg Med Chem. 2020 May 1;28(9):115423. doi: 10.1016/j.bmc.2020.115423. Epub 2020 Mar 16. Bioorg Med Chem. 2020. PMID: 32205047
Neurodevelopmental Effects of Mercury.
Oliveira CS, Nogara PA, Ardisson-Araújo DMP, Aschner M, Rocha JBT, Dórea JG. Oliveira CS, et al. Among authors: rocha jbt. Adv Neurotoxicol. 2018;2:27-86. doi: 10.1016/bs.ant.2018.03.005. Epub 2018 May 24. Adv Neurotoxicol. 2018. PMID: 32346667 Free PMC article.
556 results