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Omicron subvariant BA.5 efficiently infects lung cells.
Hoffmann M, Wong LR, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. Hoffmann M, et al. Among authors: rocha c. Nat Commun. 2023 Jun 13;14(1):3500. doi: 10.1038/s41467-023-39147-4. Nat Commun. 2023. PMID: 37311762 Free PMC article.
A tetravalent bispecific antibody outperforms the combination of its parental antibodies and neutralizes diverse SARS-CoV-2 variants.
Chiyyeadu A, Asgedom G, Bruhn M, Rocha C, Schlegel TU, Neumann T, Galla M, Vollmer Barbosa P, Hoffmann M, Ehrhardt K, Ha TC, Morgan M, Schoeder CT, Pöhlmann S, Kalinke U, Schambach A. Chiyyeadu A, et al. Among authors: rocha c. Clin Immunol. 2024 Mar;260:109902. doi: 10.1016/j.clim.2024.109902. Epub 2024 Jan 11. Clin Immunol. 2024. PMID: 38218210 Free article.
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models.
Kaiser FK, Hernandez MG, Krüger N, Englund E, Du W, Mykytyn AZ, Raadsen MP, Lamers MM, Rodrigues Ianiski F, Shamorkina TM, Snijder J, Armando F, Beythien G, Ciurkiewicz M, Schreiner T, Gruber-Dujardin E, Bleyer M, Batura O, Erffmeier L, Hinkel R, Rocha C, Mirolo M, Drabek D, Bosch BJ, Emalfarb M, Valbuena N, Tchelet R, Baumgärtner W, Saloheimo M, Pöhlmann S, Grosveld F, Haagmans BL, Osterhaus ADME. Kaiser FK, et al. Among authors: rocha c. Nat Commun. 2024 Mar 14;15(1):2319. doi: 10.1038/s41467-024-46443-0. Nat Commun. 2024. PMID: 38485931 Free PMC article.
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity.
Flury P, Breidenbach J, Krüger N, Voget R, Schäkel L, Si Y, Krasniqi V, Calistri S, Olfert M, Sylvester K, Rocha C, Ditzinger R, Rasch A, Pöhlmann S, Kronenberger T, Poso A, Rox K, Laufer SA, Müller CE, Gütschow M, Pillaiyar T. Flury P, et al. Among authors: rocha c. ACS Pharmacol Transl Sci. 2024 Jan 19;7(2):493-514. doi: 10.1021/acsptsci.3c00313. eCollection 2024 Feb 9. ACS Pharmacol Transl Sci. 2024. PMID: 38357286
Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity".
Flury P, Breidenbach J, Krüger N, Voget R, Schäkel L, Si Y, Krasniqi V, Calistri S, Olfert M, Sylvester K, Rocha C, Ditzinger R, Rasch A, Pöhlmann S, Kronenberger T, Poso A, Rox K, Laufer SA, Müller CE, Gütschow M, Pillaiyar T. Flury P, et al. Among authors: rocha c. ACS Pharmacol Transl Sci. 2024 Mar 6;7(4):1195-1196. doi: 10.1021/acsptsci.4c00095. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633592 Free article.
GMP-compliant extracellular vesicles derived from umbilical cord mesenchymal stromal cells: manufacturing and pre-clinical evaluation in ARDS treatment.
Costa-Ferro ZSM, Rocha GV, da Silva KN, Paredes BD, Loiola EC, Silva JD, Santos JLS, Dias RB, Figueira CP, de Oliveira CI, de Moura LD, Ribeiro LNM, de Paula E, Zanette DL, Rocha CAG, Rocco PRM, Souza BSF. Costa-Ferro ZSM, et al. Among authors: rocha cag. Cytotherapy. 2024 May 1:S1465-3249(24)00686-8. doi: 10.1016/j.jcyt.2024.04.074. Online ahead of print. Cytotherapy. 2024. PMID: 38762805
1,254 results