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A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in Its Interactions with α7 and α4β2 Nicotinic Acetylcholine Receptors.
Xing H, Andrud KW, Soti F, Rouchaud A, Jahn SC, Lu Z, Cho YH, Habibi S, Corsino P, Slavov S, Rocca JR, Lindstrom JM, Lukas RJ, Kem WR. Xing H, et al. Among authors: rocca jr. Mol Pharmacol. 2020 Aug;98(2):168-180. doi: 10.1124/mol.119.118786. Epub 2020 May 30. Mol Pharmacol. 2020. PMID: 32474444 Free PMC article.
Structure-activity relationships of peptides incorporating a bioactive reverse-turn heterocycle at the melanocortin receptors: identification of a 5800-fold mouse melanocortin-3 receptor (mMC3R) selective antagonist/partial agonist versus the mouse melanocortin-4 receptor (mMC4R).
Singh A, Dirain M, Witek R, Rocca JR, Edison AS, Haskell-Luevano C. Singh A, et al. Among authors: rocca jr. J Med Chem. 2013 Apr 11;56(7):2747-63. doi: 10.1021/jm301253y. Epub 2013 Mar 25. J Med Chem. 2013. PMID: 23432160 Free PMC article.
44 results