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Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target.
Istvan ES, Guerra F, Abraham M, Huang KS, Rocamora F, Zhao H, Xu L, Pasaje C, Kumpornsin K, Luth MR, Cui H, Yang T, Palomo Diaz S, Gomez-Lorenzo MG, Qahash T, Mittal N, Ottilie S, Niles J, Lee MCS, Llinas M, Kato N, Okombo J, Fidock DA, Schimmel P, Gamo FJ, Goldberg DE, Winzeler EA. Istvan ES, et al. Among authors: rocamora f. Sci Transl Med. 2023 Mar 8;15(686):eadc9249. doi: 10.1126/scitranslmed.adc9249. Epub 2023 Mar 8. Sci Transl Med. 2023. PMID: 36888694 Free PMC article.
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway.
LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA. LaMonte GM, et al. Among authors: rocamora f. Nat Commun. 2020 Apr 14;11(1):1780. doi: 10.1038/s41467-020-15440-4. Nat Commun. 2020. PMID: 32286267 Free PMC article.
Genomic Approaches to Drug Resistance in Malaria.
Rocamora F, Winzeler EA. Rocamora F, et al. Annu Rev Microbiol. 2020 Sep 8;74:761-786. doi: 10.1146/annurev-micro-012220-064343. Annu Rev Microbiol. 2020. PMID: 32905749 Review.
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum.
Rocamora F, Gupta P, Istvan ES, Luth MR, Carpenter EF, Kümpornsin K, Sasaki E, Calla J, Mittal N, Carolino K, Owen E, Llinás M, Ottilie S, Goldberg DE, Lee MCS, Winzeler EA. Rocamora F, et al. ACS Infect Dis. 2021 Apr 9;7(4):811-825. doi: 10.1021/acsinfecdis.0c00676. Epub 2021 Mar 14. ACS Infect Dis. 2021. PMID: 33715347 Free PMC article.
Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer.
Abacha YZ, Forkuo AD, Gbedema SY, Mittal N, Ottilie S, Rocamora F, Winzeler EA, van Schalkwyk DA, Kelly JM, Taylor MC, Reader J, Birkholtz LM, Lisgarten DR, Cockcroft JK, Lisgarten JN, Palmer RA, Talbert RC, Shnyder SD, Wright CW. Abacha YZ, et al. Among authors: rocamora f. Front Pharmacol. 2022 Apr 26;13:875647. doi: 10.3389/fphar.2022.875647. eCollection 2022. Front Pharmacol. 2022. PMID: 35600849 Free PMC article.
Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors.
Almaliti J, Fajtová P, Calla J, LaMonte GM, Feng M, Rocamora F, Ottilie S, Glukhov E, Boura E, Suhandynata RT, Momper JD, Gilson MK, Winzeler EA, Gerwick WH, O'Donoghue AJ. Almaliti J, et al. Among authors: rocamora f. Chemistry. 2023 Apr 6;29(20):e202203958. doi: 10.1002/chem.202203958. Epub 2023 Mar 6. Chemistry. 2023. PMID: 36617500 Free PMC article.
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.
Armstrong JF, Campo B, Alexander SPH, Arendse LB, Cheng X, Davenport AP, Faccenda E, Fidock DA, Godinez-Macias KP, Harding SD, Kato N, Lee MCS, Luth MR, Mazitschek R, Mittal N, Niles JC, Okombo J, Ottilie S, Pasaje CFA, Probst AS, Rawat M, Rocamora F, Sakata-Kato T, Southan C, Spedding M, Tye MA, Yang T, Zhao N, Davies JA. Armstrong JF, et al. Among authors: rocamora f. Br J Pharmacol. 2023 Aug;180(15):1899-1929. doi: 10.1111/bph.16144. Epub 2023 Jun 10. Br J Pharmacol. 2023. PMID: 37197802 Review.
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background.
Zhu L, Tripathi J, Rocamora FM, Miotto O, van der Pluijm R, Voss TS, Mok S, Kwiatkowski DP, Nosten F, Day NPJ, White NJ, Dondorp AM, Bozdech Z; Tracking Resistance to Artemisinin Collaboration I. Zhu L, et al. Among authors: rocamora fm. Nat Commun. 2018 Dec 4;9(1):5158. doi: 10.1038/s41467-018-07588-x. Nat Commun. 2018. PMID: 30514877 Free PMC article.
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