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Regulation of Epithelial-Mesenchymal Plasticity by the E3 Ubiquitin-Ligases in Cancer.
Cancers (Basel). 2020 Oct 23;12(11):3093. doi: 10.3390/cancers12113093.
Cancers (Basel). 2020.
PMID: 33114139
Free PMC article.
Review.
Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability.
Díaz-Díaz A, Roca-Lema D, Casas-Pais A, Romay G, Colombo G, Concha Á, Graña B, Figueroa A.
Díaz-Díaz A, et al. Among authors: roca lema d.
Cancers (Basel). 2020 Jan 15;12(1):215. doi: 10.3390/cancers12010215.
Cancers (Basel). 2020.
PMID: 31952268
Free PMC article.
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Hakin-1, a New Specific Small-Molecule Inhibitor for the E3 Ubiquitin-Ligase Hakai, Inhibits Carcinoma Growth and Progression.
Martinez-Iglesias O, Casas-Pais A, Castosa R, Díaz-Díaz A, Roca-Lema D, Concha Á, Cortés Á, Gago F, Figueroa A.
Martinez-Iglesias O, et al. Among authors: roca lema d.
Cancers (Basel). 2020 May 23;12(5):1340. doi: 10.3390/cancers12051340.
Cancers (Basel). 2020.
PMID: 32456234
Free PMC article.
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Proteomic Analysis of the E3 Ubiquitin-Ligase Hakai Highlights a Role in Plasticity of the Cytoskeleton Dynamics and in the Proteasome System.
Díaz-Díaz A, Casas-Pais A, Calamia V, Castosa R, Martinez-Iglesias O, Roca-Lema D, Santamarina I, Valladares-Ayerbes M, Calvo L, Chantada V, Figueroa A.
Díaz-Díaz A, et al. Among authors: roca lema d.
J Proteome Res. 2017 Aug 4;16(8):2773-2788. doi: 10.1021/acs.jproteome.7b00046. Epub 2017 Jul 21.
J Proteome Res. 2017.
PMID: 28675930
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Hakai overexpression effectively induces tumour progression and metastasis in vivo.
Castosa R, Martinez-Iglesias O, Roca-Lema D, Casas-Pais A, Díaz-Díaz A, Iglesias P, Santamarina I, Graña B, Calvo L, Valladares-Ayerbes M, Concha Á, Figueroa A.
Castosa R, et al. Among authors: roca lema d.
Sci Rep. 2018 Feb 22;8(1):3466. doi: 10.1038/s41598-018-21808-w.
Sci Rep. 2018.
PMID: 29472634
Free PMC article.
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Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.
Roca-Lema D, Quiroga M, Khare V, Díaz-Díaz A, Barreiro-Alonso A, Rodríguez-Alonso A, Concha Á, Romay G, Cerdán ME, Gasche C, Figueroa A.
Roca-Lema D, et al.
Sci Rep. 2022 Oct 20;12(1):17571. doi: 10.1038/s41598-022-22295-w.
Sci Rep. 2022.
PMID: 36266428
Free PMC article.
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In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells.
Roca-Lema D, Martinez-Iglesias O, Fernández de Ana Portela C, Rodríguez-Blanco A, Valladares-Ayerbes M, Díaz-Díaz A, Casas-Pais A, Prego C, Figueroa A.
Roca-Lema D, et al.
Int J Med Sci. 2019 Jan 1;16(2):231-240. doi: 10.7150/ijms.28811. eCollection 2019.
Int J Med Sci. 2019.
PMID: 30745803
Free PMC article.
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