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22 results

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Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models.
Cocco S, Leone A, Roca MS, Lombardi R, Piezzo M, Caputo R, Ciardiello C, Costantini S, Bruzzese F, Sisalli MJ, Budillon A, De Laurentiis M. Cocco S, et al. Among authors: roca ms. J Transl Med. 2022 Jun 27;20(1):290. doi: 10.1186/s12967-022-03462-z. J Transl Med. 2022. PMID: 35761360 Free PMC article.
Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
Avallone A, Piccirillo MC, Delrio P, Pecori B, Di Gennaro E, Aloj L, Tatangelo F, D'Angelo V, Granata C, Cavalcanti E, Maurea N, Maiolino P, Bianco F, Montano M, Silvestro L, Terranova Barberio M, Roca MS, Di Maio M, Marone P, Botti G, Petrillo A, Daniele G, Lastoria S, Iaffaioli VR, Romano G, Caracò C, Muto P, Gallo C, Perrone F, Budillon A. Avallone A, et al. Among authors: roca ms. BMC Cancer. 2014 Nov 24;14:875. doi: 10.1186/1471-2407-14-875. BMC Cancer. 2014. PMID: 25421252 Free PMC article. Clinical Trial.
Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway.
Leone A, Roca MS, Ciardiello C, Terranova-Barberio M, Vitagliano C, Ciliberto G, Mancini R, Di Gennaro E, Bruzzese F, Budillon A. Leone A, et al. Among authors: roca ms. Free Radic Biol Med. 2015 Dec;89:287-99. doi: 10.1016/j.freeradbiomed.2015.07.155. Epub 2015 Sep 26. Free Radic Biol Med. 2015. PMID: 26409771
Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression.
Terranova-Barberio M, Roca MS, Zotti AI, Leone A, Bruzzese F, Vitagliano C, Scogliamiglio G, Russo D, D'Angelo G, Franco R, Budillon A, Di Gennaro E. Terranova-Barberio M, et al. Among authors: roca ms. Oncotarget. 2016 Feb 16;7(7):7715-31. doi: 10.18632/oncotarget.6802. Oncotarget. 2016. PMID: 26735339 Free PMC article.
Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression.
Ciardiello C, Roca MS, Noto A, Bruzzese F, Moccia T, Vitagliano C, Di Gennaro E, Ciliberto G, Roscilli G, Aurisicchio L, Marra E, Mancini R, Budillon A, Leone A. Ciardiello C, et al. Among authors: roca ms. Oncotarget. 2016 Apr 12;7(15):19559-74. doi: 10.18632/oncotarget.7195. Oncotarget. 2016. PMID: 26862736 Free PMC article.
A standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges.
Lanuti P, Simeone P, Rotta G, Almici C, Avvisati G, Azzaro R, Bologna G, Budillon A, Di Cerbo M, Di Gennaro E, Di Martino ML, Diodato A, Doretto P, Ercolino E, Falda A, Gregorj C, Leone A, Losa F, Malara N, Marini M, Mastroroberto P, Mollace V, Morelli M, Muggianu E, Musolino G, Neva A, Pierdomenico L, Pinna S, Piovani G, Roca MS, Russo D, Scotti L, Tirindelli MC, Trunzo V, Venturella R, Vitagliano C, Zullo F, Marchisio M, Miscia S. Lanuti P, et al. Among authors: roca ms. Sci Rep. 2018 Apr 11;8(1):5823. doi: 10.1038/s41598-018-24234-0. Sci Rep. 2018. PMID: 29643468 Free PMC article.
22 results