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TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B. Arseni D, et al. Among authors: robinson ac. Nature. 2023 Aug;620(7975):898-903. doi: 10.1038/s41586-023-06405-w. Epub 2023 Aug 2. Nature. 2023. PMID: 37532939 Free PMC article.
Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72.
Mann DM, Rollinson S, Robinson A, Bennion Callister J, Thompson JC, Snowden JS, Gendron T, Petrucelli L, Masuda-Suzukake M, Hasegawa M, Davidson Y, Pickering-Brown S. Mann DM, et al. Acta Neuropathol Commun. 2013 Oct 14;1:68. doi: 10.1186/2051-5960-1-68. Acta Neuropathol Commun. 2013. PMID: 24252525 Free PMC article.
Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72.
Davidson YS, Barker H, Robinson AC, Thompson JC, Harris J, Troakes C, Smith B, Al-Saraj S, Shaw C, Rollinson S, Masuda-Suzukake M, Hasegawa M, Pickering-Brown S, Snowden JS, Mann DM. Davidson YS, et al. Among authors: robinson ac. Acta Neuropathol Commun. 2014 Jun 20;2:70. doi: 10.1186/2051-5960-2-70. Acta Neuropathol Commun. 2014. PMID: 24950788 Free PMC article.
Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene.
Baborie A, Griffiths TD, Jaros E, Perry R, McKeith IG, Burn DJ, Masuda-Suzukake M, Hasegawa M, Rollinson S, Pickering-Brown S, Robinson AC, Davidson YS, Mann DM. Baborie A, et al. Among authors: robinson ac. Neuropathol Appl Neurobiol. 2015 Aug;41(5):601-12. doi: 10.1111/nan.12178. Epub 2015 Apr 30. Neuropathol Appl Neurobiol. 2015. PMID: 25185840 Free PMC article.
Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau.
Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DMA, Iwatsubo T, Hasegawa M. Taniguchi-Watanabe S, et al. Acta Neuropathol. 2016 Feb;131(2):267-280. doi: 10.1007/s00401-015-1503-3. Epub 2015 Nov 4. Acta Neuropathol. 2016. PMID: 26538150 Free PMC article.
Neurodegeneration in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9orf72 is linked to TDP-43 pathology and not associated with aggregated forms of dipeptide repeat proteins.
Davidson Y, Robinson AC, Liu X, Wu D, Troakes C, Rollinson S, Masuda-Suzukake M, Suzuki G, Nonaka T, Shi J, Tian J, Hamdalla H, Ealing J, Richardson A, Jones M, Pickering-Brown S, Snowden JS, Hasegawa M, Mann DM. Davidson Y, et al. Among authors: robinson ac. Neuropathol Appl Neurobiol. 2016 Apr;42(3):242-54. doi: 10.1111/nan.12292. Epub 2015 Dec 7. Neuropathol Appl Neurobiol. 2016. PMID: 26538301 Free PMC article.
Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy.
Behrouzi R, Liu X, Wu D, Robinson AC, Tanaguchi-Watanabe S, Rollinson S, Shi J, Tian J, Hamdalla HH, Ealing J, Richardson A, Jones M, Pickering-Brown S, Davidson YS, Strong MJ, Hasegawa M, Snowden JS, Mann DM. Behrouzi R, et al. Among authors: robinson ac. Acta Neuropathol Commun. 2016 Mar 31;4:33. doi: 10.1186/s40478-016-0301-z. Acta Neuropathol Commun. 2016. PMID: 27036121 Free PMC article.
Comparison of Common and Disease-Specific Post-translational Modifications of Pathological Tau Associated With a Wide Range of Tauopathies.
Kametani F, Yoshida M, Matsubara T, Murayama S, Saito Y, Kawakami I, Onaya M, Tanaka H, Kakita A, Robinson AC, Mann DMA, Hasegawa M. Kametani F, et al. Among authors: robinson ac. Front Neurosci. 2020 Nov 4;14:581936. doi: 10.3389/fnins.2020.581936. eCollection 2020. Front Neurosci. 2020. PMID: 33250706 Free PMC article.
213 results