Robertson GT - Search Results

1

Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.

Ma Z, He S, Yuan Y, Zhuang Z, Liu Y, Wang H, Chen J, Xu X, Ding C, Molodtsov V, Lin W, Robertson GT, Weiss WJ, Pulse M, Nguyen P, Duncan L, Doyle T, Ebright RH, Lynch AS. Ma Z, et al. Among authors: robertson gt. J Med Chem. 2022 Mar 24;65(6):4481-4495. doi: 10.1021/acs.jmedchem.1c02045. Epub 2022 Feb 17. J Med Chem. 2022. PMID: 35175750 Free PMC article.

2

New C25 carbamate rifamycin derivatives are resistant to inactivation by ADP-ribosyl transferases.

Combrink KD, Denton DA, Harran S, Ma Z, Chapo K, Yan D, Bonventre E, Roche ED, Doyle TB, Robertson GT, Lynch AS. Combrink KD, et al. Among authors: robertson gt. Bioorg Med Chem Lett. 2007 Jan 15;17(2):522-6. doi: 10.1016/j.bmcl.2006.10.016. Epub 2006 Oct 12. Bioorg Med Chem Lett. 2007. PMID: 17070048

3

In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: studies of the mode of action in Staphylococcus aureus.

Robertson GT, Bonventre EJ, Doyle TB, Du Q, Duncan L, Morris TW, Roche ED, Yan D, Lynch AS. Robertson GT, et al. Antimicrob Agents Chemother. 2008 Jul;52(7):2313-23. doi: 10.1128/AAC.01649-07. Epub 2008 Apr 28. Antimicrob Agents Chemother. 2008. PMID: 18443108 Free PMC article.

4

Bacterial and fungal biofilm infections.

Lynch AS, Robertson GT. Lynch AS, et al. Among authors: robertson gt. Annu Rev Med. 2008;59:415-28. doi: 10.1146/annurev.med.59.110106.132000. Annu Rev Med. 2008. PMID: 17937586 Review.

5

Use of an efflux-deficient streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic resistance to antimicrobial agents.

Robertson GT, Doyle TB, Lynch AS. Robertson GT, et al. Antimicrob Agents Chemother. 2005 Nov;49(11):4781-3. doi: 10.1128/AAC.49.11.4781-4783.2005. Antimicrob Agents Chemother. 2005. PMID: 16251330 Free PMC article.

6

In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: microbiology profiling studies with staphylococci and streptococci.

Robertson GT, Bonventre EJ, Doyle TB, Du Q, Duncan L, Morris TW, Roche ED, Yan D, Lynch AS. Robertson GT, et al. Antimicrob Agents Chemother. 2008 Jul;52(7):2324-34. doi: 10.1128/AAC.01651-07. Epub 2008 Apr 28. Antimicrob Agents Chemother. 2008. PMID: 18443106 Free PMC article.

7

A Novel indole compound that inhibits Pseudomonas aeruginosa growth by targeting MreB is a substrate for MexAB-OprM.

Robertson GT, Doyle TB, Du Q, Duncan L, Mdluli KE, Lynch AS. Robertson GT, et al. J Bacteriol. 2007 Oct;189(19):6870-81. doi: 10.1128/JB.00805-07. Epub 2007 Jul 20. J Bacteriol. 2007. PMID: 17644596 Free PMC article.

8

Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities.

Boshoff HIM, Young K, Ahn YM, Yadav VD, Crowley BM, Yang L, Su J, Oh S, Arora K, Andrews J, Manikkam M, Sutphin M, Smith AJ, Weiner DM, Piazza MK, Fleegle JD, Gomez F, Dayao EK, Prideaux B, Zimmerman M, Kaya F, Sarathy J, Tan VY, Via LE, Tschirret-Guth R, Lenaerts AJ, Robertson GT, Dartois V, Olsen DB, Barry CE 3rd. Boshoff HIM, et al. Among authors: robertson gt. ACS Infect Dis. 2024 May 10;10(5):1679-1695. doi: 10.1021/acsinfecdis.4c00025. Epub 2024 Apr 6. ACS Infect Dis. 2024. PMID: 38581700

9

Use of multiple pharmacodynamic measures to deconstruct the Nix-TB regimen in a short-course murine model of tuberculosis.

Lyons MA, Obregon-Henao A, Ramey ME, Bauman AA, Pauly S, Rossmassler K, Reid J, Karger B, Walter ND, Robertson GT. Lyons MA, et al. Among authors: robertson gt. Antimicrob Agents Chemother. 2024 May 2;68(5):e0101023. doi: 10.1128/aac.01010-23. Epub 2024 Mar 19. Antimicrob Agents Chemother. 2024. PMID: 38501805 Free PMC article.

10

A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides.

Ali MZ, Dutt TS, MacNeill A, Walz A, Patterson J, Pearce C, Lam H, Henao-Tamayo M, Lee RE, Liu J, Robertson GT, Hickey AJ, Meibohm B, Gonzalez-Juarrero M. Ali MZ, et al. Among authors: robertson gt. bioRxiv [Preprint]. 2023 Nov 16:2023.11.16.567434. doi: 10.1101/2023.11.16.567434. bioRxiv. 2023. PMID: 38014249 Free PMC article. Preprint.

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