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Target-based selection of flavonoids for neurodegenerative disorders.
Jones QR, Warford J, Rupasinghe HP, Robertson GS. Jones QR, et al. Among authors: robertson gs. Trends Pharmacol Sci. 2012 Nov;33(11):602-10. doi: 10.1016/j.tips.2012.08.002. Epub 2012 Sep 12. Trends Pharmacol Sci. 2012. PMID: 22980637 Review.
The cytokine and endocannabinoid systems are co-regulated by NF-κB p65/RelA in cell culture and transgenic mouse models of Huntington's disease and in striatal tissue from Huntington's disease patients.
Laprairie RB, Warford JR, Hutchings S, Robertson GS, Kelly ME, Denovan-Wright EM. Laprairie RB, et al. Among authors: robertson gs. J Neuroimmunol. 2014 Feb 15;267(1-2):61-72. doi: 10.1016/j.jneuroim.2013.12.008. Epub 2013 Dec 12. J Neuroimmunol. 2014. PMID: 24360910
New methods for multiple sclerosis drug discovery.
Warford J, Robertson GS. Warford J, et al. Among authors: robertson gs. Expert Opin Drug Discov. 2011 Jul;6(7):689-99. doi: 10.1517/17460441.2011.573783. Epub 2011 Mar 30. Expert Opin Drug Discov. 2011. PMID: 22650977
Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis.
Soundararajan R, Wishart AD, Rupasinghe HP, Arcellana-Panlilio M, Nelson CM, Mayne M, Robertson GS. Soundararajan R, et al. Among authors: robertson gs. J Biol Chem. 2008 Jan 25;283(4):2231-45. doi: 10.1074/jbc.M703583200. Epub 2007 Nov 20. J Biol Chem. 2008. PMID: 18032389 Free article.
Targeting apoptosis to treat multiple sclerosis.
Hebb AL, Moore CS, Bhan V, Robertson GS. Hebb AL, et al. Among authors: robertson gs. Curr Drug Discov Technol. 2008 Mar;5(1):75-7. doi: 10.2174/157016308783769432. Curr Drug Discov Technol. 2008. PMID: 18537570 Review.
235 results