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Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.
Varma VR, Wang Y, An Y, Varma S, Bilgel M, Doshi J, Legido-Quigley C, Delgado JC, Oommen AM, Roberts JA, Wong DF, Davatzikos C, Resnick SM, Troncoso JC, Pletnikova O, O'Brien R, Hak E, Baak BN, Pfeiffer R, Baloni P, Mohmoudiandehkordi S, Nho K, Kaddurah-Daouk R, Bennett DA, Gadalla SM, Thambisetty M. Varma VR, et al. Among authors: roberts ja. PLoS Med. 2021 May 27;18(5):e1003615. doi: 10.1371/journal.pmed.1003615. eCollection 2021 May. PLoS Med. 2021. PMID: 34043628 Free PMC article.
Blood Metabolite Signature of Metabolic Syndrome Implicates Alterations in Amino Acid Metabolism: Findings from the Baltimore Longitudinal Study of Aging (BLSA) and the Tsuruoka Metabolomics Cohort Study (TMCS).
Roberts JA, Varma VR, Huang CW, An Y, Oommen A, Tanaka T, Ferrucci L, Elango P, Takebayashi T, Harada S, Iida M, Thambisetty M. Roberts JA, et al. Int J Mol Sci. 2020 Feb 13;21(4):1249. doi: 10.3390/ijms21041249. Int J Mol Sci. 2020. PMID: 32070008 Free PMC article.
Abnormal brain cholesterol homeostasis in Alzheimer's disease-a targeted metabolomic and transcriptomic study.
Varma VR, Büşra Lüleci H, Oommen AM, Varma S, Blackshear CT, Griswold ME, An Y, Roberts JA, O'Brien R, Pletnikova O, Troncoso JC, Bennett DA, Çakır T, Legido-Quigley C, Thambisetty M. Varma VR, et al. Among authors: roberts ja. NPJ Aging Mech Dis. 2021 Jun 1;7(1):11. doi: 10.1038/s41514-021-00064-9. NPJ Aging Mech Dis. 2021. PMID: 34075056 Free PMC article.
Acid ceramidase promotes senescent cell survival.
Munk R, Anerillas C, Rossi M, Tsitsipatis D, Martindale JL, Herman AB, Yang JH, Roberts JA, Varma VR, Pandey PR, Thambisetty M, Gorospe M, Abdelmohsen K. Munk R, et al. Among authors: roberts ja. Aging (Albany NY). 2021 Jun 8;13(12):15750-15769. doi: 10.18632/aging.203170. Epub 2021 Jun 8. Aging (Albany NY). 2021. PMID: 34102611 Free PMC article.
A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets.
Roberts JA, Varma VR, An Y, Varma S, Candia J, Fantoni G, Tiwari V, Anerillas C, Williamson A, Saito A, Loeffler T, Schilcher I, Moaddel R, Khadeer M, Lovett J, Tanaka T, Pletnikova O, Troncoso JC, Bennett DA, Albert MS, Yu K, Niu M, Haroutunian V, Zhang B, Peng J, Croteau DL, Resnick SM, Gorospe M, Bohr VA, Ferrucci L, Thambisetty M. Roberts JA, et al. Sci Adv. 2021 Nov 12;7(46):eabi8178. doi: 10.1126/sciadv.abi8178. Epub 2021 Nov 10. Sci Adv. 2021. PMID: 34757788 Free PMC article.
Serum Proteomic Signatures of Common Health Outcomes among Older Adults.
Roberts JA, Basu-Roy S, Shin J, Varma VR, Williamson A, Blackshear C, Griswold ME, Candia J, Elango P, Karikkineth AC, Tanaka T, Ferrucci L, Thambisetty M. Roberts JA, et al. Gerontology. 2024;70(3):269-278. doi: 10.1159/000534753. Epub 2024 Jan 12. Gerontology. 2024. PMID: 38219723
Identification and characterisation of functional Kir6.1-containing ATP-sensitive potassium channels in the cardiac ventricular sarcolemmal membrane.
Brennan S, Chen S, Makwana S, Esposito S, McGuinness LR, Alnaimi AIM, Sims MW, Patel M, Aziz Q, Ojake L, Roberts JA, Sharma P, Lodwick D, Tinker A, Barrett-Jolley R, Dart C, Rainbow RD. Brennan S, et al. Among authors: roberts ja. Br J Pharmacol. 2024 May 19. doi: 10.1111/bph.16390. Online ahead of print. Br J Pharmacol. 2024. PMID: 38763521
1,474 results