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Page 1
CXCR2 inhibition enables NASH-HCC immunotherapy.
Leslie J, Mackey JBG, Jamieson T, Ramon-Gil E, Drake TM, Fercoq F, Clark W, Gilroy K, Hedley A, Nixon C, Luli S, Laszczewska M, Pinyol R, Esteban-Fabró R, Willoughby CE, Haber PK, Andreu-Oller C, Rahbari M, Fan C, Pfister D, Raman S, Wilson N, Müller M, Collins A, Geh D, Fuller A, McDonald D, Hulme G, Filby A, Cortes-Lavaud X, Mohamed NE, Ford CA, Raffo Iraolagoitia XL, McFarlane AJ, McCain MV, Ridgway RA, Roberts EW, Barry ST, Graham GJ, Heikenwälder M, Reeves HL, Llovet JM, Carlin LM, Bird TG, Sansom OJ, Mann DA. Leslie J, et al. Among authors: roberts ew. Gut. 2022 Apr 27;71(10):2093-106. doi: 10.1136/gutjnl-2021-326259. Online ahead of print. Gut. 2022. PMID: 35477863 Free PMC article.
Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis.
Hewitt RJ, Puttur F, Gaboriau DCA, Fercoq F, Fresquet M, Traves WJ, Yates LL, Walker SA, Molyneaux PL, Kemp SV, Nicholson AG, Rice A, Roberts E, Lennon R, Carlin LM, Byrne AJ, Maher TM, Lloyd CM. Hewitt RJ, et al. Nat Commun. 2023 Sep 27;14(1):6039. doi: 10.1038/s41467-023-41621-y. Nat Commun. 2023. PMID: 37758700 Free PMC article.
Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis.
Ntala C, Salji M, Salmond J, Officer L, Teodosio AV, Blomme A, McGhee EJ, Powley I, Ahmad I, Kruithof-de Julio M, Thalmann G, Roberts E, Goodyear CS, Jamaspishvili T, Berman DM, Carlin LM, Le Quesne J, Leung HY. Ntala C, et al. Eur Urol Open Sci. 2021 May 25;29:19-29. doi: 10.1016/j.euros.2021.05.001. eCollection 2021 Jul. Eur Urol Open Sci. 2021. PMID: 34337530 Free PMC article.
A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies.
Scott JI, Mendive-Tapia L, Gordon D, Barth ND, Thompson EJ, Cheng Z, Taggart D, Kitamura T, Bravo-Blas A, Roberts EW, Juarez-Jimenez J, Michel J, Piet B, de Vries IJ, Verdoes M, Dawson J, Carragher NO, Connor RAO, Akram AR, Frame M, Serrels A, Vendrell M. Scott JI, et al. Among authors: roberts ew. Nat Commun. 2022 May 2;13(1):2366. doi: 10.1038/s41467-022-29691-w. Nat Commun. 2022. PMID: 35501326 Free PMC article.
Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness.
Pirillo C, Birch F, Tissot FS, Anton SG, Haltalli M, Tini V, Kong I, Piot C, Partridge B, Pospori C, Keeshan K, Santamaria S, Hawkins E, Falini B, Marra A, Duarte D, Lee CF, Roberts E, Lo Celso C. Pirillo C, et al. Blood Adv. 2022 May 24;6(10):3126-3141. doi: 10.1182/bloodadvances.2021004321. Blood Adv. 2022. PMID: 35157757 Free PMC article.
Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation.
Pirillo C, Al Khalidi S, Sims A, Devlin R, Zhao H, Pinto R, Jasim S, Shearer PA, Shergold AL, Donnelly H, Bravo-Blas A, Loney C, Perona-Wright G, Hutchinson E, Roberts EW. Pirillo C, et al. Among authors: roberts ew. Sci Immunol. 2023 Jul 21;8(85):eadg8249. doi: 10.1126/sciimmunol.adg8249. Epub 2023 Jul 21. Sci Immunol. 2023. PMID: 37478193
55 results