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Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses.
Anderluzzi G, Schmidt ST, Cunliffe R, Woods S, Roberts CW, Veggi D, Ferlenghi I, O'Hagan DT, Baudner BC, Perrie Y. Anderluzzi G, et al. Among authors: roberts cw. J Control Release. 2021 Feb 10;330:933-944. doi: 10.1016/j.jconrel.2020.10.066. Epub 2020 Nov 2. J Control Release. 2021. PMID: 33152394 Free article.
Immunogenetics of Toxoplasma gondii informs vaccine design.
Henriquez FL, Woods S, Cong H, McLeod R, Roberts CW. Henriquez FL, et al. Among authors: roberts cw. Trends Parasitol. 2010 Nov;26(11):550-5. doi: 10.1016/j.pt.2010.06.004. Epub 2010 Jun 26. Trends Parasitol. 2010. PMID: 20580611 Review.
Toxoplasma gondii HLA-B*0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite burden in HLA-B*0702 mice.
Cong H, Mui EJ, Witola WH, Sidney J, Alexander J, Sette A, Maewal A, El Bissati K, Zhou Y, Suzuki Y, Lee D, Woods S, Sommerville C, Henriquez FL, Roberts CW, McLeod R. Cong H, et al. Among authors: roberts cw. Hum Immunol. 2012 Jan;73(1):1-10. doi: 10.1016/j.humimm.2011.10.006. Epub 2011 Oct 12. Hum Immunol. 2012. PMID: 22027386 Free PMC article.
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target.
Wilkinson C, McPhillie MJ, Zhou Y, Woods S, Afanador GA, Rawson S, Khaliq F, Prigge ST, Roberts CW, Rice DW, McLeod R, Fishwick CW, Muench SP. Wilkinson C, et al. Among authors: roberts cw. Bioorg Med Chem Lett. 2014 Feb 1;24(3):911-6. doi: 10.1016/j.bmcl.2013.12.066. Epub 2013 Dec 22. Bioorg Med Chem Lett. 2014. PMID: 24398298 Free PMC article.
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
El Bissati K, Chentoufi AA, Krishack PA, Zhou Y, Woods S, Dubey JP, Vang L, Lykins J, Broderick KE, Mui E, Suzuki Y, Sa Q, Bi S, Cardona N, Verma SK, Fraczek L, Reardon CA, Sidney J, Alexander J, Sette A, Vedvick T, Fox C, Guderian JA, Reed S, Roberts CW, McLeod R. El Bissati K, et al. Among authors: roberts cw. JCI Insight. 2016 Sep 22;1(15):e85955. doi: 10.1172/jci.insight.85955. JCI Insight. 2016. PMID: 27699241 Free PMC article.
289 results