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The Hedgehog signal transduction network.
Robbins DJ, Fei DL, Riobo NA. Robbins DJ, et al. Sci Signal. 2012 Oct 16;5(246):re6. doi: 10.1126/scisignal.2002906. Sci Signal. 2012. PMID: 23074268 Free PMC article. Review.
Repurposing an old anti-fungal drug as a Hedgehog inhibitor.
Giambelli C, Fei DL, Wang H, Robbins DJ. Giambelli C, et al. Among authors: robbins dj. Protein Cell. 2010 May;1(5):417-8. doi: 10.1007/s13238-010-0063-5. Protein Cell. 2010. PMID: 21203953 Free PMC article. No abstract available.
Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity.
Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Singh S, et al. Among authors: robbins dj. Cancer Res. 2011 Jul 1;71(13):4454-63. doi: 10.1158/0008-5472.CAN-10-2313. Epub 2011 May 12. Cancer Res. 2011. PMID: 21565978 Free PMC article.
The hedgehog processing pathway is required for NSCLC growth and survival.
Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, Lam WL, Dmitrovsky E, Capobianco AJ, Robbins DJ. Rodriguez-Blanco J, et al. Among authors: robbins dj. Oncogene. 2013 May 2;32(18):2335-45. doi: 10.1038/onc.2012.243. Epub 2012 Jun 25. Oncogene. 2013. PMID: 22733134 Free PMC article.
Hedgehog signaling regulates bladder cancer growth and tumorigenicity.
Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ. Fei DL, et al. Among authors: robbins dj. Cancer Res. 2012 Sep 1;72(17):4449-58. doi: 10.1158/0008-5472.CAN-11-4123. Epub 2012 Jul 19. Cancer Res. 2012. PMID: 22815529 Free PMC article.
All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
Busch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E. Busch AM, et al. Among authors: robbins dj. Cancer Biol Ther. 2014 Apr;15(4):463-72. doi: 10.4161/cbt.27821. Epub 2014 Feb 4. Cancer Biol Ther. 2014. PMID: 24496080 Free PMC article.
165 results