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Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair.
Tempka D, Tokarz P, Chmielewska K, Kluska M, Pietrzak J, Rygielska Ż, Virág L, Robaszkiewicz A. Tempka D, et al. Among authors: robaszkiewicz a. Redox Biol. 2018 May;15:316-326. doi: 10.1016/j.redox.2017.12.017. Epub 2017 Dec 29. Redox Biol. 2018. PMID: 29306194 Free PMC article.
LPS protects macrophages from AIF-independent parthanatos by downregulation of PARP1 expression, induction of SOD2 expression, and a metabolic shift to aerobic glycolysis.
Regdon Z, Robaszkiewicz A, Kovács K, Rygielska Ż, Hegedűs C, Bodoor K, Szabó É, Virág L. Regdon Z, et al. Among authors: robaszkiewicz a. Free Radic Biol Med. 2019 Feb 1;131:184-196. doi: 10.1016/j.freeradbiomed.2018.11.034. Epub 2018 Nov 28. Free Radic Biol Med. 2019. PMID: 30502458
48 results