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Passive Alzheimer's immunotherapy: A promising or uncertain option?
Høilund-Carlsen PF, Revheim ME, Costa T, Alavi A, Kepp KP, Sensi SL, Perry G, Robakis NK, Barrio JR, Vissel B. Høilund-Carlsen PF, et al. Among authors: robakis nk. Ageing Res Rev. 2023 Sep;90:101996. doi: 10.1016/j.arr.2023.101996. Epub 2023 Jul 5. Ageing Res Rev. 2023. PMID: 37414156 Review.
Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.
Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, Jun YW. Kwak M, et al. Among authors: robakis nk. Nat Cell Biol. 2022 Dec;24(12):1739-1753. doi: 10.1038/s41556-022-01031-6. Epub 2022 Dec 1. Nat Cell Biol. 2022. PMID: 36456828 Free PMC article.
The amyloid cascade hypothesis: an updated critical review.
Kepp KP, Robakis NK, Høilund-Carlsen PF, Sensi SL, Vissel B. Kepp KP, et al. Among authors: robakis nk. Brain. 2023 Oct 3;146(10):3969-3990. doi: 10.1093/brain/awad159. Brain. 2023. PMID: 37183523 Review.
The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes.
Kepp KP, Sensi SL, Johnsen KB, Barrio JR, Høilund-Carlsen PF, Neve RL, Alavi A, Herrup K, Perry G, Robakis NK, Vissel B, Espay AJ. Kepp KP, et al. Among authors: robakis nk. J Alzheimers Dis. 2023;94(2):497-507. doi: 10.3233/JAD-230099. J Alzheimers Dis. 2023. PMID: 37334596
Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village.
Høilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Høilund-Carlsen PF, et al. Among authors: robakis nk. Ageing Res Rev. 2024 Jan;93:102173. doi: 10.1016/j.arr.2023.102173. Epub 2023 Dec 15. Ageing Res Rev. 2024. PMID: 38104639 Free article. Review.
Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-aspartate receptor.
Al Rahim M, Yoon Y, Dimovasili C, Shao Z, Huang Q, Zhang E, Kezunovic N, Chen L, Schaffner A, Huntley GW, Ubarretxena-Belandia I, Georgakopoulos A, Robakis NK. Al Rahim M, et al. Among authors: robakis nk. Brain Commun. 2020 Jul 20;2(2):fcaa100. doi: 10.1093/braincomms/fcaa100. eCollection 2020. Brain Commun. 2020. PMID: 33005890 Free PMC article.
PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival.
Yoon Y, Voloudakis G, Doran N, Zhang E, Dimovasili C, Chen L, Shao Z, Darmanis S, Tang C, Tang J, Wang VX, Hof PR, Robakis NK, Georgakopoulos A. Yoon Y, et al. Among authors: robakis nk. Mol Psychiatry. 2021 Jun;26(6):1996-2012. doi: 10.1038/s41380-020-0812-7. Epub 2020 Jun 15. Mol Psychiatry. 2021. PMID: 32541930 Free PMC article.
Substrate interaction inhibits γ-secretase production of amyloid-β peptides.
Zhao J, Xiao Y, Liu X, Kim S, Wu X, Barros M, Zhuang R, Hou X, Zhang Y, Robakis NK, Li YM, Dordick JS, Ubarretxena-Belandia I, Wang C. Zhao J, et al. Among authors: robakis nk. Chem Commun (Camb). 2020 Feb 27;56(17):2578-2581. doi: 10.1039/c9cc09170j. Chem Commun (Camb). 2020. PMID: 32016207 Free PMC article.
137 results