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Acarbose presents in vitro and in vivo antileishmanial activity against Leishmania infantum and is a promising therapeutic candidate against visceral leishmaniasis.
Costa RR, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Mendonça DVC, Freitas CS, Lage DP, Martins VT, Antinarelli LMR, Machado AS, Bandeira RS, Ludolf F, Santos TTO, Brito RCF, Humbert MV, Menezes-Souza D, Duarte MC, Chávez-Fumagalli MA, Roatt BM, Coimbra ES, Coelho EAF. Costa RR, et al. Among authors: roatt bm. Med Microbiol Immunol. 2021 Jun;210(2-3):133-147. doi: 10.1007/s00430-021-00707-4. Epub 2021 Apr 18. Med Microbiol Immunol. 2021. PMID: 33870453 Free PMC article.
Performance of LBSap vaccine after intradermal challenge with L. infantum and saliva of Lu. longipalpis: immunogenicity and parasitological evaluation.
Roatt BM, Aguiar-Soares RD, Vitoriano-Souza J, Coura-Vital W, Braga SL, Corrêa-Oliveira R, Martins-Filho OA, Teixeira-Carvalho A, de Lana M, Figueiredo Gontijo N, Marques MJ, Giunchetti RC, Reis AB. Roatt BM, et al. PLoS One. 2012;7(11):e49780. doi: 10.1371/journal.pone.0049780. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189161 Free PMC article.
Dogs immunized with LBSap vaccine displayed high levels of IL-12 and IL-10 cytokines and CCL4, CCL5 and CXCL8 chemokines in the dermis.
Vitoriano-Souza J, Moreira Nd, Menezes-Souza D, Roatt BM, de Oliveira Aguiar-Soares RD, Siqueira-Mathias FA, de Oliveira Cardoso JM, Giunchetti RC, de Sá RG, Corrêa-Oliveira R, Carneiro CM, Reis AB. Vitoriano-Souza J, et al. Among authors: roatt bm. Mol Immunol. 2013 Dec;56(4):540-8. doi: 10.1016/j.molimm.2013.05.231. Epub 2013 Aug 1. Mol Immunol. 2013. PMID: 23911411 Free PMC article.
Molecular diagnosis of canine visceral leishmaniasis: a comparative study of three methods using skin and spleen from dogs with natural Leishmania infantum infection.
Reis LE, Coura-Vital W, Roatt BM, Bouillet LÉ, Ker HG, Fortes de Brito RC, Resende Dde M, Carneiro M, Giunchetti RC, Marques MJ, Carneiro CM, Reis AB. Reis LE, et al. Among authors: roatt bm. Vet Parasitol. 2013 Nov 8;197(3-4):498-503. doi: 10.1016/j.vetpar.2013.07.006. Epub 2013 Jul 19. Vet Parasitol. 2013. PMID: 23953760 Free article.
Evaluation of a prototype flow cytometry test for serodiagnosis of canine visceral leishmaniasis.
Ker HG, Coura-Vital W, Aguiar-Soares RD, Roatt BM, das Dores Moreira N, Carneiro CM, Machado EM, Teixeira-Carvalho A, Martins-Filho OA, Giunchetti RC, Araújo MS, Coelho EA, da Silveira-Lemos D, Reis AB. Ker HG, et al. Among authors: roatt bm. Clin Vaccine Immunol. 2013 Dec;20(12):1792-8. doi: 10.1128/CVI.00575-13. Epub 2013 Oct 9. Clin Vaccine Immunol. 2013. PMID: 24108778 Free PMC article.
Clinical forms of canine visceral Leishmaniasis in naturally Leishmania infantum-infected dogs and related myelogram and hemogram changes.
Nicolato Rde C, de Abreu RT, Roatt BM, Aguiar-Soares RD, Reis LE, Carvalho Md, Carneiro CM, Giunchetti RC, Bouillet LE, Lemos DS, Coura-Vital W, Reis AB. Nicolato Rde C, et al. Among authors: roatt bm. PLoS One. 2013 Dec 23;8(12):e82947. doi: 10.1371/journal.pone.0082947. eCollection 2013. PLoS One. 2013. PMID: 24376612 Free PMC article.
LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4⁺ and CD8⁺) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis.
Aguiar-Soares RD, Roatt BM, Ker HG, Moreira Nd, Mathias FA, Cardoso JM, Gontijo NF, Bruna-Romero O, Teixeira-Carvalho A, Martins-Filho OA, Corrêa-Oliveira R, Giunchetti RC, Reis AB. Aguiar-Soares RD, et al. Among authors: roatt bm. Parasit Vectors. 2014 Feb 7;7:61. doi: 10.1186/1756-3305-7-61. Parasit Vectors. 2014. PMID: 24507702 Free PMC article.
118 results