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Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML.
Blood. 2023 Mar 2;141(9):1023-1035. doi: 10.1182/blood.2021015246.
Blood. 2023.
PMID: 35981498
Free article.
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
Kempf JM, Weser S, Bartoschek MD, Metzeler KH, Vick B, Herold T, Völse K, Mattes R, Scholz M, Wange LE, Festini M, Ugur E, Roas M, Weigert O, Bultmann S, Leonhardt H, Schotta G, Hiddemann W, Jeremias I, Spiekermann K.
Kempf JM, et al. Among authors: roas m.
Sci Rep. 2021 Mar 12;11(1):5838. doi: 10.1038/s41598-021-84708-6.
Sci Rep. 2021.
PMID: 33712646
Free PMC article.
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Long noncoding RNA HOTAIR is upregulated in an aggressive subgroup of gastrointestinal stromal tumors (GIST) and mediates the establishment of gene-specific DNA methylation patterns.
Bure I, Geer S, Knopf J, Roas M, Henze S, Ströbel P, Agaimy A, Wiemann S, Hoheisel JD, Hartmann A, Haller F, Moskalev EA.
Bure I, et al. Among authors: roas m.
Genes Chromosomes Cancer. 2018 Nov;57(11):584-597. doi: 10.1002/gcc.22672. Epub 2018 Sep 24.
Genes Chromosomes Cancer. 2018.
PMID: 30248209
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The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma.
Ruh M, Stemmler MP, Frisch I, Fuchs K, van Roey R, Kleemann J, Roas M, Schuhwerk H, Eccles RL, Agaimy A, Baumhoer D, Berx G, Müller F, Brabletz T, Brabletz S.
Ruh M, et al. Among authors: roas m.
J Pathol. 2021 Jun;254(2):199-211. doi: 10.1002/path.5659. Epub 2021 May 6.
J Pathol. 2021.
PMID: 33675037
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