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Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons.
Perdices-Lopez C, Avendaño MS, Barroso A, Gaytán F, Ruiz-Pino F, Vázquez MJ, Leon S, Song YB, Sobrino V, Heras V, Romero-Ruiz A, Roa J, Mayor F Jr, Murga C, Pinilla L, Kaiser UB, Tena-Sempere M. Perdices-Lopez C, et al. Among authors: roa j. Metabolism. 2022 Apr;129:155141. doi: 10.1016/j.metabol.2022.155141. Epub 2022 Jan 22. Metabolism. 2022. PMID: 35074314 Free PMC article.
Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse.
León S, García-Galiano D, Ruiz-Pino F, Barroso A, Manfredi-Lozano M, Romero-Ruiz A, Roa J, Vázquez MJ, Gaytan F, Blomenrohr M, van Duin M, Pinilla L, Tena-Sempere M. León S, et al. Among authors: roa j. Endocrinology. 2014 Aug;155(8):2953-65. doi: 10.1210/en.2014-1030. Epub 2014 May 13. Endocrinology. 2014. PMID: 24823392
Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice.
Leon S, Velasco I, Vázquez MJ, Barroso A, Beiroa D, Heras V, Ruiz-Pino F, Manfredi-Lozano M, Romero-Ruiz A, Sanchez-Garrido MA, Dieguez C, Pinilla L, Roa J, Nogueiras R, Tena-Sempere M. Leon S, et al. Among authors: roa j. Metabolism. 2018 Oct;87:87-97. doi: 10.1016/j.metabol.2018.07.003. Epub 2018 Jul 31. Metabolism. 2018. PMID: 30075164
Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling.
Roa J, Barroso A, Ruiz-Pino F, Vázquez MJ, Seoane-Collazo P, Martínez-Sanchez N, García-Galiano D, Ilhan T, Pineda R, León S, Manfredi-Lozano M, Heras V, Poutanen M, Castellano JM, Gaytan F, Diéguez C, Pinilla L, López M, Tena-Sempere M. Roa J, et al. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10758-E10767. doi: 10.1073/pnas.1802053115. Epub 2018 Oct 22. Proc Natl Acad Sci U S A. 2018. PMID: 30348767 Free PMC article.
Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis.
Velasco I, León S, Barroso A, Ruiz-Pino F, Heras V, Torres E, León M, Ruohonen ST, García-Galiano D, Romero-Ruiz A, Sánchez-Garrido MA, Ohlsson C, Castellano JM, Roa J, Poutanen M, Pinilla L, Vázquez MJ, Tena-Sempere M. Velasco I, et al. Among authors: roa j. Metabolism. 2019 Sep;98:84-94. doi: 10.1016/j.metabol.2019.06.007. Epub 2019 Jun 19. Metabolism. 2019. PMID: 31226351
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3.
Heras V, Sangiao-Alvarellos S, Manfredi-Lozano M, Sanchez-Tapia MJ, Ruiz-Pino F, Roa J, Lara-Chica M, Morrugares-Carmona R, Jouy N, Abreu AP, Prevot V, Belsham D, Vazquez MJ, Calzado MA, Pinilla L, Gaytan F, Latronico AC, Kaiser UB, Castellano JM, Tena-Sempere M. Heras V, et al. Among authors: roa j. PLoS Biol. 2019 Nov 7;17(11):e3000532. doi: 10.1371/journal.pbio.3000532. eCollection 2019 Nov. PLoS Biol. 2019. PMID: 31697675 Free PMC article.
Neuropeptide Control of Puberty: Beyond Kisspeptins.
Barroso A, Roa J, Tena-Sempere M. Barroso A, et al. Among authors: roa j. Semin Reprod Med. 2019 Jul;37(4):155-165. doi: 10.1055/s-0039-3400967. Epub 2020 Jan 23. Semin Reprod Med. 2019. PMID: 31972860 Review.
Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty.
Heras V, Castellano JM, Fernandois D, Velasco I, Rodríguez-Vazquez E, Roa J, Vazquez MJ, Ruiz-Pino F, Rubio M, Pineda R, Torres E, Avendaño MS, Paredes A, Pinilla L, Belsham D, Diéguez C, Gaytán F, Casals N, López M, Tena-Sempere M. Heras V, et al. Among authors: roa j. Cell Metab. 2020 Dec 1;32(6):951-966.e8. doi: 10.1016/j.cmet.2020.10.001. Epub 2020 Oct 19. Cell Metab. 2020. PMID: 33080217 Free article.
519 results