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301 results

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Page 1
Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.
Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G; PROPPR Study Group. Holcomb JB, et al. Among authors: rizoli s. JAMA. 2015 Feb 3;313(5):471-82. doi: 10.1001/jama.2015.12. JAMA. 2015. PMID: 25647203 Free PMC article. Clinical Trial.
Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: design, rationale and implementation.
Baraniuk S, Tilley BC, del Junco DJ, Fox EE, van Belle G, Wade CE, Podbielski JM, Beeler AM, Hess JR, Bulger EM, Schreiber MA, Inaba K, Fabian TC, Kerby JD, Cohen MJ, Miller CN, Rizoli S, Scalea TM, O'Keeffe T, Brasel KJ, Cotton BA, Muskat P, Holcomb JB; PROPPR Study Group. Baraniuk S, et al. Among authors: rizoli s. Injury. 2014 Sep;45(9):1287-95. doi: 10.1016/j.injury.2014.06.001. Epub 2014 Jun 10. Injury. 2014. PMID: 24996573 Free PMC article. Clinical Trial.
Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: experience from the Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR) trial.
Novak DJ, Bai Y, Cooke RK, Marques MB, Fontaine MJ, Gottschall JL, Carey PM, Scanlan RM, Fiebig EW, Shulman IA, Nelson JM, Flax S, Duncan V, Daniel-Johnson JA, Callum JL, Holcomb JB, Fox EE, Baraniuk S, Tilley BC, Schreiber MA, Inaba K, Rizoli S, Podbielski JM, Cotton BA, Hess JR; PROPPR Study Group. Novak DJ, et al. Among authors: rizoli s. Transfusion. 2015 Jun;55(6):1331-9. doi: 10.1111/trf.13098. Epub 2015 Mar 30. Transfusion. 2015. PMID: 25823522 Free PMC article.
The hyperfibrinolytic phenotype is the most lethal and resource intense presentation of fibrinolysis in massive transfusion patients.
Taylor JR 3rd, Fox EE, Holcomb JB, Rizoli S, Inaba K, Schreiber MA, Brasel K, Scalea TM, Wade CE, Bulger E, Cotton BA; PROPPR Study Group. Taylor JR 3rd, et al. Among authors: rizoli s. J Trauma Acute Care Surg. 2018 Jan;84(1):25-30. doi: 10.1097/TA.0000000000001699. J Trauma Acute Care Surg. 2018. PMID: 28914713 Free PMC article. Clinical Trial.
Earlier time to hemostasis is associated with decreased mortality and rate of complications: Results from the Pragmatic Randomized Optimal Platelet and Plasma Ratio trial.
Chang R, Kerby JD, Kalkwarf KJ, Van Belle G, Fox EE, Cotton BA, Cohen MJ, Schreiber MA, Brasel K, Bulger EM, Inaba K, Rizoli S, Podbielski JM, Wade CE, Holcomb JB; PROPPR Study Group. Chang R, et al. Among authors: rizoli s. J Trauma Acute Care Surg. 2019 Aug;87(2):342-349. doi: 10.1097/TA.0000000000002263. J Trauma Acute Care Surg. 2019. PMID: 31349348 Free PMC article. Clinical Trial.
Group A emergency-release plasma in trauma patients requiring massive transfusion.
de Roulet A, Kerby JD, Weinberg JA, Lewis RH Jr, Hudgins JP, Shulman IA, Fox EE, Holcomb JB, Brasel KJ, Bulger EM, Cohen MJ, Cotton BA, Fabian TC, O'Keeffe T, Rizoli S, Scalea TM, Schreiber MA, Inaba K; PROPPR Study Group. de Roulet A, et al. Among authors: rizoli s. J Trauma Acute Care Surg. 2020 Dec;89(6):1061-1067. doi: 10.1097/TA.0000000000002903. J Trauma Acute Care Surg. 2020. PMID: 32890339 Free PMC article. Clinical Trial.
Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury.
Rowell SE, Meier EN, McKnight B, Kannas D, May S, Sheehan K, Bulger EM, Idris AH, Christenson J, Morrison LJ, Frascone RJ, Bosarge PL, Colella MR, Johannigman J, Cotton BA, Callum J, McMullan J, Dries DJ, Tibbs B, Richmond NJ, Weisfeldt ML, Tallon JM, Garrett JS, Zielinski MD, Aufderheide TP, Gandhi RR, Schlamp R, Robinson BRH, Jui J, Klein L, Rizoli S, Gamber M, Fleming M, Hwang J, Vincent LE, Williams C, Hendrickson A, Simonson R, Klotz P, Sopko G, Witham W, Ferrara M, Schreiber MA. Rowell SE, et al. Among authors: rizoli s. JAMA. 2020 Sep 8;324(10):961-974. doi: 10.1001/jama.2020.8958. JAMA. 2020. PMID: 32897344 Free PMC article. Clinical Trial.
301 results