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Parasite Metalo-aminopeptidases as Targets in Human Infectious Diseases.
Aguado ME, Izquierdo M, González-Matos M, Varela AC, Méndez Y, Del Rivero MA, Rivera DG, González-Bacerio J. Aguado ME, et al. Among authors: rivera dg. Curr Drug Targets. 2023;24(5):416-461. doi: 10.2174/1389450124666230224140724. Curr Drug Targets. 2023. PMID: 36825701 Review.
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
González-Bacerio J, Maluf SEC, Méndez Y, Pascual I, Florent I, Melo PMS, Budu A, Ferreira JC, Moreno E, Carmona AK, Rivera DG, Alonso Del Rivero M, Gazarini ML. González-Bacerio J, et al. Among authors: rivera dg. Bioorg Med Chem. 2017 Sep 1;25(17):4628-4636. doi: 10.1016/j.bmc.2017.06.047. Epub 2017 Jul 4. Bioorg Med Chem. 2017. PMID: 28728898
Multicomponent polysaccharide-protein bioconjugation in the development of antibacterial glycoconjugate vaccine candidates.
Méndez Y, Chang J, Humpierre AR, Zanuy A, Garrido R, Vasco AV, Pedroso J, Santana D, Rodríguez LM, García-Rivera D, Valdés Y, Vérez-Bencomo V, Rivera DG. Méndez Y, et al. Among authors: rivera dg. Chem Sci. 2018 Jan 19;9(9):2581-2588. doi: 10.1039/c7sc05467j. eCollection 2018 Mar 7. Chem Sci. 2018. PMID: 29719713 Free PMC article.
Multicomponent Reactions in Ligation and Bioconjugation Chemistry.
Reguera L, Méndez Y, Humpierre AR, Valdés O, Rivera DG. Reguera L, et al. Among authors: rivera dg. Acc Chem Res. 2018 Jun 19;51(6):1475-1486. doi: 10.1021/acs.accounts.8b00126. Epub 2018 May 25. Acc Chem Res. 2018. PMID: 29799718
Discovery of potent and selective inhibitors of the Escherichia coli M1-aminopeptidase via multicomponent solid-phase synthesis of tetrazole-peptidomimetics.
Méndez Y, De Armas G, Pérez I, Rojas T, Valdés-Tresanco ME, Izquierdo M, Alonso Del Rivero M, Álvarez-Ginarte YM, Valiente PA, Soto C, de León L, Vasco AV, Scott WL, Westermann B, González-Bacerio J, Rivera DG. Méndez Y, et al. Among authors: rivera dg. Eur J Med Chem. 2019 Feb 1;163:481-499. doi: 10.1016/j.ejmech.2018.11.074. Epub 2018 Dec 1. Eur J Med Chem. 2019. PMID: 30544037 Free article.
Expanding the Scope of Ugi Multicomponent Bioconjugation to Produce Pneumococcal Multivalent Glycoconjugates as Vaccine Candidates.
Humpierre AR, Zanuy A, Saenz M, Garrido R, Vasco AV, Pérez-Nicado R, Soroa-Milán Y, Santana-Mederos D, Westermann B, Vérez-Bencomo V, Méndez Y, García-Rivera D, Rivera DG. Humpierre AR, et al. Among authors: rivera dg. Bioconjug Chem. 2020 Sep 16;31(9):2231-2240. doi: 10.1021/acs.bioconjchem.0c00423. Epub 2020 Sep 2. Bioconjug Chem. 2020. PMID: 32809806
94 results