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Two different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich's ataxia.
Dis Model Mech. 2016 Jun 1;9(6):647-57. doi: 10.1242/dmm.024273. Epub 2016 Apr 14.
Dis Model Mech. 2016.
PMID: 27079523
Free PMC article.
Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice.
Mollá B, Muñoz-Lasso DC, Riveiro F, Bolinches-Amorós A, Pallardó FV, Fernandez-Vilata A, de la Iglesia-Vaya M, Palau F, Gonzalez-Cabo P.
Mollá B, et al. Among authors: riveiro f.
Front Mol Neurosci. 2017 Aug 30;10:264. doi: 10.3389/fnmol.2017.00264. eCollection 2017.
Front Mol Neurosci. 2017.
PMID: 28912677
Free PMC article.
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