Riva A - Search Results

1

Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.

Lopusna K, Nowialis P, Opavska J, Abraham A, Riva A, Haney SL, Opavsky R. Lopusna K, et al. Among authors: riva a. J Biol Chem. 2021 Jan-Jun;296:100285. doi: 10.1016/j.jbc.2021.100285. Epub 2021 Jan 13. J Biol Chem. 2021. PMID: 33450231 Free PMC article.

2

Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.

Nowialis P, Lopusna K, Opavska J, Haney SL, Abraham A, Sheng P, Riva A, Natarajan A, Guryanova O, Simpson M, Hlady R, Xie M, Opavsky R. Nowialis P, et al. Among authors: riva a. Nat Commun. 2019 Sep 26;10(1):4374. doi: 10.1038/s41467-019-12355-7. Nat Commun. 2019. PMID: 31558711 Free PMC article.

3

Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.

Lopusna K, Nowialis P, Opavska J, Abraham A, Riva A, Opavsky R. Lopusna K, et al. Among authors: riva a. EBioMedicine. 2021 Jan;63:103191. doi: 10.1016/j.ebiom.2020.103191. Epub 2021 Jan 6. EBioMedicine. 2021. PMID: 33418509 Free PMC article.

4

DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks.

Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Román HL, Posada LM, Gunaratne C, Li J, Dupéré-Richer D, Bennett RL, Pondugula S, Riva A, Cogle CR, Opavsky R, Law BK, Bhaduri-McIntosh S, Kubicek S, Staber PB, Licht JD, Bird JE, Guryanova OA. Venugopal K, et al. Among authors: riva a. Clin Cancer Res. 2022 Feb 15;28(4):756-769. doi: 10.1158/1078-0432.CCR-21-2863. Clin Cancer Res. 2022. PMID: 34716195 Free PMC article.

5

A Mutation in Histone H2B Represents a New Class of Oncogenic Driver.

Bennett RL, Bele A, Small EC, Will CM, Nabet B, Oyer JA, Huang X, Ghosh RP, Grzybowski AT, Yu T, Zhang Q, Riva A, Lele TP, Schatz GC, Kelleher NL, Ruthenburg AJ, Liphardt J, Licht JD. Bennett RL, et al. Among authors: riva a. Cancer Discov. 2019 Oct;9(10):1438-1451. doi: 10.1158/2159-8290.CD-19-0393. Epub 2019 Jul 23. Cancer Discov. 2019. PMID: 31337617 Free PMC article.

6

PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia.

Li J, Hlavka-Zhang J, Shrimp JH, Piper C, Dupéré-Richér D, Roth JS, Jing D, Casellas Román HL, Troche C, Swaroop A, Kulis M, Oyer JA, Will CM, Shen M, Riva A, Bennett RL, Ferrando AA, Hall MD, Lock RB, Licht JD. Li J, et al. Among authors: riva a. Cancer Discov. 2022 Jan;12(1):186-203. doi: 10.1158/2159-8290.CD-20-1771. Epub 2021 Aug 20. Cancer Discov. 2022. PMID: 34417224

7

Multiplex mapping of chromatin accessibility and DNA methylation within targeted single molecules identifies epigenetic heterogeneity in neural stem cells and glioblastoma.

Nabilsi NH, Deleyrolle LP, Darst RP, Riva A, Reynolds BA, Kladde MP. Nabilsi NH, et al. Among authors: riva a. Genome Res. 2014 Feb;24(2):329-39. doi: 10.1101/gr.161737.113. Epub 2013 Oct 8. Genome Res. 2014. PMID: 24105770 Free PMC article.

8

UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.

Ezponda T, Dupéré-Richer D, Will CM, Small EC, Varghese N, Patel T, Nabet B, Popovic R, Oyer J, Bulic M, Zheng Y, Huang X, Shah MY, Maji S, Riva A, Occhionorelli M, Tonon G, Kelleher N, Keats J, Licht JD. Ezponda T, et al. Among authors: riva a. Cell Rep. 2017 Oct 17;21(3):628-640. doi: 10.1016/j.celrep.2017.09.078. Cell Rep. 2017. PMID: 29045832 Free PMC article.

9

The murine Pbx1-d lupus susceptibility allele accelerates mesenchymal stem cell differentiation and impairs their immunosuppressive function.

Lu S, Zeumer L, Sorensen H, Yang H, Ng Y, Yu F, Riva A, Croker B, Wallet S, Morel L. Lu S, et al. Among authors: riva a. J Immunol. 2015 Jan 1;194(1):43-55. doi: 10.4049/jimmunol.1401851. J Immunol. 2015. PMID: 25416808

10

HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.

Morozov VM, Riva A, Sarwar S, Kim WJ, Li J, Zhou L, Licht JD, Daaka Y, Ishov AM. Morozov VM, et al. Among authors: riva a. Nucleic Acids Res. 2023 Oct 27;51(19):10194-10217. doi: 10.1093/nar/gkad700. Nucleic Acids Res. 2023. PMID: 37638746 Free PMC article.

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