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The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis.
Flores-Costa R, Alcaraz-Quiles J, Titos E, López-Vicario C, Casulleras M, Duran-Güell M, Rius B, Diaz A, Hall K, Shea C, Sarno R, Currie M, Masferrer JL, Clària J. Flores-Costa R, et al. Among authors: rius b. Br J Pharmacol. 2018 Mar;175(6):953-967. doi: 10.1111/bph.14137. Epub 2018 Jan 31. Br J Pharmacol. 2018. PMID: 29281143 Free PMC article.
Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides.
López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Clària J. López-Vicario C, et al. Among authors: rius b. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):536-41. doi: 10.1073/pnas.1422590112. Epub 2014 Dec 30. Proc Natl Acad Sci U S A. 2015. PMID: 25550510 Free PMC article.
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