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Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis.
Skendros P, Mitsios A, Chrysanthopoulou A, Mastellos DC, Metallidis S, Rafailidis P, Ntinopoulou M, Sertaridou E, Tsironidou V, Tsigalou C, Tektonidou M, Konstantinidis T, Papagoras C, Mitroulis I, Germanidis G, Lambris JD, Ritis K. Skendros P, et al. Among authors: ritis k. J Clin Invest. 2020 Nov 2;130(11):6151-6157. doi: 10.1172/JCI141374. J Clin Invest. 2020. PMID: 32759504 Free PMC article. Clinical Trial.
C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome.
Kambas K, Markiewski MM, Pneumatikos IA, Rafail SS, Theodorou V, Konstantonis D, Kourtzelis I, Doumas MN, Magotti P, Deangelis RA, Lambris JD, Ritis KD. Kambas K, et al. Among authors: ritis kd. J Immunol. 2008 Jun 1;180(11):7368-75. doi: 10.4049/jimmunol.180.11.7368. J Immunol. 2008. PMID: 18490736 Free PMC article.
Regulation of the autophagic machinery in human neutrophils.
Mitroulis I, Kourtzelis I, Kambas K, Rafail S, Chrysanthopoulou A, Speletas M, Ritis K. Mitroulis I, et al. Among authors: ritis k. Eur J Immunol. 2010 May;40(5):1461-72. doi: 10.1002/eji.200940025. Eur J Immunol. 2010. PMID: 20162553 Free article.
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