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Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection.
PLoS Pathog. 2022 May 5;18(5):e1010471. doi: 10.1371/journal.ppat.1010471. eCollection 2022 May.
PLoS Pathog. 2022.
PMID: 35512020
Free PMC article.
Expanded human NK cells from lung cancer patients sensitize patients' PDL1-negative tumors to PD1-blockade therapy.
Poznanski SM, Ritchie TM, Fan IY, El-Sayes A, Portillo AL, Ben-Avi R, Rojas EA, Chew MV, Shargall Y, Ashkar AA.
Poznanski SM, et al. Among authors: ritchie tm.
J Immunother Cancer. 2021 Jan;9(1):e001933. doi: 10.1136/jitc-2020-001933.
J Immunother Cancer. 2021.
PMID: 33479024
Free PMC article.
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Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment.
Poznanski SM, Singh K, Ritchie TM, Aguiar JA, Fan IY, Portillo AL, Rojas EA, Vahedi F, El-Sayes A, Xing S, Butcher M, Lu Y, Doxey AC, Schertzer JD, Hirte HW, Ashkar AA.
Poznanski SM, et al. Among authors: ritchie tm.
Cell Metab. 2021 Jun 1;33(6):1205-1220.e5. doi: 10.1016/j.cmet.2021.03.023. Epub 2021 Apr 13.
Cell Metab. 2021.
PMID: 33852875
Free article.
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Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors.
Portillo AL, Hogg R, Poznanski SM, Rojas EA, Cashell NJ, Hammill JA, Chew MV, Shenouda MM, Ritchie TM, Cao QT, Hirota JA, Dhesy-Thind S, Bramson JL, Ashkar AA.
Portillo AL, et al. Among authors: ritchie tm.
iScience. 2021 May 24;24(6):102619. doi: 10.1016/j.isci.2021.102619. eCollection 2021 Jun 25.
iScience. 2021.
PMID: 34159300
Free PMC article.
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Charting a killer course to the solid tumor: strategies to recruit and activate NK cells in the tumor microenvironment.
Portillo AL, Monteiro JK, Rojas EA, Ritchie TM, Gillgrass A, Ashkar AA.
Portillo AL, et al. Among authors: ritchie tm.
Front Immunol. 2023 Nov 8;14:1286750. doi: 10.3389/fimmu.2023.1286750. eCollection 2023.
Front Immunol. 2023.
PMID: 38022679
Free PMC article.
Review.
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Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity.
Balint E, Feng E, Giles EC, Ritchie TM, Qian AS, Vahedi F, Montemarano A, Portillo AL, Monteiro JK, Trigatti BL, Ashkar AA.
Balint E, et al. Among authors: ritchie tm.
Nat Commun. 2024 Feb 5;15(1):896. doi: 10.1038/s41467-023-44667-0.
Nat Commun. 2024.
PMID: 38316762
Free PMC article.
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