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Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium.
Pentinmikko N, Iqbal S, Mana M, Andersson S, Cognetta AB 3rd, Suciu RM, Roper J, Luopajärvi K, Markelin E, Gopalakrishnan S, Smolander OP, Naranjo S, Saarinen T, Juuti A, Pietiläinen K, Auvinen P, Ristimäki A, Gupta N, Tammela T, Jacks T, Sabatini DM, Cravatt BF, Yilmaz ÖH, Katajisto P. Pentinmikko N, et al. Among authors: ristimaki a. Nature. 2019 Jul;571(7765):398-402. doi: 10.1038/s41586-019-1383-0. Epub 2019 Jul 10. Nature. 2019. PMID: 31292548 Free PMC article.
Vascular endothelial growth factor in human preterm lung.
Lassus P, Ristimäki A, Ylikorkala O, Viinikka L, Andersson S. Lassus P, et al. Among authors: ristimaki a. Am J Respir Crit Care Med. 1999 May;159(5 Pt 1):1429-33. doi: 10.1164/ajrccm.159.5.9806073. Am J Respir Crit Care Med. 1999. PMID: 10228106
Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.
Udd L, Katajisto P, Rossi DJ, Lepistö A, Lahesmaa AM, Ylikorkala A, Järvinen HJ, Ristimäki AP, Mäkelä TP. Udd L, et al. Among authors: ristimaki ap. Gastroenterology. 2004 Oct;127(4):1030-7. doi: 10.1053/j.gastro.2004.07.059. Gastroenterology. 2004. PMID: 15480979
Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling.
Lähde M, Heino S, Högström J, Kaijalainen S, Anisimov A, Flanagan D, Kallio P, Leppänen VM, Ristimäki A, Ritvos O, Wu K, Tammela T, Hodder M, Sansom OJ, Alitalo K. Lähde M, et al. Among authors: ristimaki a. Gastroenterology. 2021 Jan;160(1):245-259. doi: 10.1053/j.gastro.2020.09.011. Epub 2020 Sep 14. Gastroenterology. 2021. PMID: 32941878
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Flanagan DJ, Pentinmikko N, Luopajärvi K, Willis NJ, Gilroy K, Raven AP, Mcgarry L, Englund JI, Webb AT, Scharaw S, Nasreddin N, Hodder MC, Ridgway RA, Minnee E, Sphyris N, Gilchrist E, Najumudeen AK, Romagnolo B, Perret C, Williams AC, Clevers H, Nummela P, Lähde M, Alitalo K, Hietakangas V, Hedley A, Clark W, Nixon C, Kirschner K, Jones EY, Ristimäki A, Leedham SJ, Fish PV, Vincent JP, Katajisto P, Sansom OJ. Flanagan DJ, et al. Among authors: ristimaki a. Nature. 2021 Jun;594(7863):430-435. doi: 10.1038/s41586-021-03525-z. Epub 2021 Jun 2. Nature. 2021. PMID: 34079124 Free PMC article.
WNT2 activation through proximal germline deletion predisposes to small intestinal neuroendocrine tumors and intestinal adenocarcinomas.
Aavikko M, Kaasinen E, Andersson N, Pentinmikko N, Sulo P, Donner I, Pihlajamaa P, Kuosmanen A, Bramante S, Katainen R, Sipilä LJ, Martin S, Arola J, Carpén O, Heiskanen I, Mecklin JP, Taipale J, Ristimäki A, Lehti K, Gucciardo E, Katajisto P, Schalin-Jäntti C, Vahteristo P, Aaltonen LA. Aavikko M, et al. Among authors: ristimaki a. Hum Mol Genet. 2021 Nov 30;30(24):2429-2440. doi: 10.1093/hmg/ddab206. Hum Mol Genet. 2021. PMID: 34274970 Free PMC article.
Contribution of allelic imbalance to colorectal cancer.
Palin K, Pitkänen E, Turunen M, Sahu B, Pihlajamaa P, Kivioja T, Kaasinen E, Välimäki N, Hänninen UA, Cajuso T, Aavikko M, Tuupanen S, Kilpivaara O, van den Berg L, Kondelin J, Tanskanen T, Katainen R, Grau M, Rauanheimo H, Plaketti RM, Taira A, Sulo P, Hartonen T, Dave K, Schmierer B, Botla S, Sokolova M, Vähärautio A, Gladysz K, Ongen H, Dermitzakis E, Bramsen JB, Ørntoft TF, Andersen CL, Ristimäki A, Lepistö A, Renkonen-Sinisalo L, Mecklin JP, Taipale J, Aaltonen LA. Palin K, et al. Among authors: ristimaki a. Nat Commun. 2018 Sep 10;9(1):3664. doi: 10.1038/s41467-018-06132-1. Nat Commun. 2018. PMID: 30202008 Free PMC article.
267 results