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Conformational dynamics and enzyme evolution.
Petrović D, Risso VA, Kamerlin SCL, Sanchez-Ruiz JM. Petrović D, et al. Among authors: risso va. J R Soc Interface. 2018 Jul;15(144):20180330. doi: 10.1098/rsif.2018.0330. J R Soc Interface. 2018. PMID: 30021929 Free PMC article. Review.
Thermostable and promiscuous Precambrian proteins.
Risso VA, Gavira JA, Sanchez-Ruiz JM. Risso VA, et al. Environ Microbiol. 2014 Jun;16(6):1485-9. doi: 10.1111/1462-2920.12319. Environ Microbiol. 2014. PMID: 25009840 No abstract available.
Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history.
Risso VA, Manssour-Triedo F, Delgado-Delgado A, Arco R, Barroso-delJesus A, Ingles-Prieto A, Godoy-Ruiz R, Gavira JA, Gaucher EA, Ibarra-Molero B, Sanchez-Ruiz JM. Risso VA, et al. Mol Biol Evol. 2015 Feb;32(2):440-55. doi: 10.1093/molbev/msu312. Epub 2014 Nov 12. Mol Biol Evol. 2015. PMID: 25392342 Free PMC article.
Engineering ancestral protein hyperstability.
Romero-Romero ML, Risso VA, Martinez-Rodriguez S, Ibarra-Molero B, Sanchez-Ruiz JM. Romero-Romero ML, et al. Among authors: risso va. Biochem J. 2016 Oct 15;473(20):3611-3620. doi: 10.1042/BCJ20160532. Epub 2016 Aug 15. Biochem J. 2016. PMID: 27528732
De novo active sites for resurrected Precambrian enzymes.
Risso VA, Martinez-Rodriguez S, Candel AM, Krüger DM, Pantoja-Uceda D, Ortega-Muñoz M, Santoyo-Gonzalez F, Gaucher EA, Kamerlin SCL, Bruix M, Gavira JA, Sanchez-Ruiz JM. Risso VA, et al. Nat Commun. 2017 Jul 18;8:16113. doi: 10.1038/ncomms16113. Nat Commun. 2017. PMID: 28719578 Free PMC article.
Cooperativity and flexibility in enzyme evolution.
Pabis A, Risso VA, Sanchez-Ruiz JM, Kamerlin SC. Pabis A, et al. Among authors: risso va. Curr Opin Struct Biol. 2018 Feb;48:83-92. doi: 10.1016/j.sbi.2017.10.020. Epub 2017 Nov 12. Curr Opin Struct Biol. 2018. PMID: 29141202 Free article. Review.
38 results