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Page 1
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
Riscal R, Schrepfer E, Arena G, Cissé MY, Bellvert F, Heuillet M, Rambow F, Bonneil E, Sabourdy F, Vincent C, Ait-Arsa I, Levade T, Thibaut P, Marine JC, Portais JC, Sarry JE, Le Cam L, Linares LK. Riscal R, et al. Mol Cell. 2016 Jun 16;62(6):890-902. doi: 10.1016/j.molcel.2016.04.033. Epub 2016 Jun 2. Mol Cell. 2016. PMID: 27264869 Free article.
Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.
Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L. Arena G, et al. Among authors: riscal r. Mol Cell. 2018 Feb 15;69(4):594-609.e8. doi: 10.1016/j.molcel.2018.01.023. Mol Cell. 2018. PMID: 29452639 Free PMC article.
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.
Goguet-Rubio P, Seyran B, Gayte L, Bernex F, Sutter A, Delpech H, Linares LK, Riscal R, Repond C, Rodier G, Kirsh O, Touhami J, Noel J, Vincent C, Pirot N, Pavlovic G, Herault Y, Sitbon M, Pellerin L, Sardet C, Lacroix M, Le Cam L. Goguet-Rubio P, et al. Among authors: riscal r. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):11004-9. doi: 10.1073/pnas.1602751113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621431 Free PMC article.
Chromatin-bound MDM2, a new player in metabolism.
Riscal R, Le Cam L, Linares LK. Riscal R, et al. Mol Cell Oncol. 2016 Jul 15;3(5):e1210560. doi: 10.1080/23723556.2016.1210560. eCollection 2016. Mol Cell Oncol. 2016. PMID: 27857973 Free PMC article.
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma.
Cissé MY, Pyrdziak S, Firmin N, Gayte L, Heuillet M, Bellvert F, Fuentes M, Delpech H, Riscal R, Arena G, Chibon F, Le Gellec S, Maran-Gonzalez A, Chateau MC, Theillet C, Carrere S, Portais JC, Le Cam L, Linares LK. Cissé MY, et al. Among authors: riscal r. Sci Transl Med. 2020 Jun 10;12(547):eaay2163. doi: 10.1126/scitranslmed.aay2163. Sci Transl Med. 2020. PMID: 32522803
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.
Boutzen H, Saland E, Larrue C, de Toni F, Gales L, Castelli FA, Cathebas M, Zaghdoudi S, Stuani L, Kaoma T, Riscal R, Yang G, Hirsch P, David M, De Mas-Mansat V, Delabesse E, Vallar L, Delhommeau F, Jouanin I, Ouerfelli O, Le Cam L, Linares LK, Junot C, Portais JC, Vergez F, Récher C, Sarry JE. Boutzen H, et al. Among authors: riscal r. J Exp Med. 2016 Apr 4;213(4):483-97. doi: 10.1084/jem.20150736. Epub 2016 Mar 7. J Exp Med. 2016. PMID: 26951332 Free PMC article. Clinical Trial.
Even Cancer Cells Watch Their Cholesterol!
Riscal R, Skuli N, Simon MC. Riscal R, et al. Mol Cell. 2019 Oct 17;76(2):220-231. doi: 10.1016/j.molcel.2019.09.008. Epub 2019 Oct 2. Mol Cell. 2019. PMID: 31586545 Free PMC article. Review.
17 results