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A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Maruggi G, Mallett CP, Westerbeck JW, Chen T, Lofano G, Friedrich K, Qu L, Sun JT, McAuliffe J, Kanitkar A, Arrildt KT, Wang KF, McBee I, McCoy D, Terry R, Rowles A, Abrahim MA, Ringenberg MA, Gains MJ, Spickler C, Xie X, Zou J, Shi PY, Dutt T, Henao-Tamayo M, Ragan I, Bowen RA, Johnson R, Nuti S, Luisi K, Ulmer JB, Steff AM, Jalah R, Bertholet S, Stokes AH, Yu D. Maruggi G, et al. Among authors: ringenberg ma. Mol Ther. 2022 May 4;30(5):1897-1912. doi: 10.1016/j.ymthe.2022.01.001. Epub 2022 Jan 3. Mol Ther. 2022. PMID: 34990810 Free PMC article. Clinical Trial.
Nonclinical safety assessment of repeated administration and biodistribution of a novel rabies self-amplifying mRNA vaccine in rats.
Stokes A, Pion J, Binazon O, Laffont B, Bigras M, Dubois G, Blouin K, Young JK, Ringenberg MA, Ben Abdeljelil N, Haruna J, Rodriguez LA. Stokes A, et al. Among authors: ringenberg ma. Regul Toxicol Pharmacol. 2020 Jun;113:104648. doi: 10.1016/j.yrtph.2020.104648. Epub 2020 Mar 30. Regul Toxicol Pharmacol. 2020. PMID: 32240713
Repeated Dose Toxicity Study and Developmental and Reproductive Toxicology Studies of a Respiratory Syncytial Virus Candidate Vaccine in Rabbits and Rats.
Stokes AH, Franklin K, Fisher DE, Posobiec LM, Binazon O, Tripathi N, Ringenberg MA, Charlap J, Ziejewski MK, Vemireddi V, Khanna Weiss P, Majumdar R, Bouzya B, Donner MN, Rodriguez LA, Baumeister J. Stokes AH, et al. Among authors: ringenberg ma. Int J Toxicol. 2021 Mar-Apr;40(2):125-142. doi: 10.1177/1091581820985782. Epub 2021 Feb 1. Int J Toxicol. 2021. PMID: 33517807
MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses.
Yu JW, Hoffman S, Beal AM, Dykon A, Ringenberg MA, Hughes AC, Dare L, Anderson AD, Finger J, Kasparcova V, Rickard D, Berger SB, Ramanjulu J, Emery JG, Gough PJ, Bertin J, Foley KP. Yu JW, et al. Among authors: ringenberg ma. PLoS One. 2015 May 12;10(5):e0127083. doi: 10.1371/journal.pone.0127083. eCollection 2015. PLoS One. 2015. PMID: 25965667 Free PMC article.
Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance imaging assessment.
Olzinski AR, Turner GH, Bernard RE, Karr H, Cornejo CA, Aravindhan K, Hoang B, Ringenberg MA, Qin P, Goodman KB, Willette RN, Macphee CH, Jucker BM, Sehon CA, Gough PJ. Olzinski AR, et al. Among authors: ringenberg ma. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):253-9. doi: 10.1161/ATVBAHA.109.198812. Epub 2009 Dec 3. Arterioscler Thromb Vasc Biol. 2010. PMID: 19965779
Meningeal osteosarcoma in a dog.
Ringenberg MA, Neitzel LE, Zachary JF. Ringenberg MA, et al. Vet Pathol. 2000 Nov;37(6):653-5. doi: 10.1354/vp.37-6-653. Vet Pathol. 2000. PMID: 11105956