Rimpelä AK - Search Results

1

Pharmacokinetic aspects of retinal drug delivery.

Del Amo EM, Rimpelä AK, Heikkinen E, Kari OK, Ramsay E, Lajunen T, Schmitt M, Pelkonen L, Bhattacharya M, Richardson D, Subrizi A, Turunen T, Reinisalo M, Itkonen J, Toropainen E, Casteleijn M, Kidron H, Antopolsky M, Vellonen KS, Ruponen M, Urtti A. Del Amo EM, et al. Among authors: rimpela ak. Prog Retin Eye Res. 2017 Mar;57:134-185. doi: 10.1016/j.preteyeres.2016.12.001. Epub 2016 Dec 24. Prog Retin Eye Res. 2017. PMID: 28028001 Free article. Review.

2

Implications of melanin binding in ocular drug delivery.

Rimpelä AK, Reinisalo M, Hellinen L, Grazhdankin E, Kidron H, Urtti A, Del Amo EM. Rimpelä AK, et al. Adv Drug Deliv Rev. 2018 Feb 15;126:23-43. doi: 10.1016/j.addr.2017.12.008. Epub 2017 Dec 13. Adv Drug Deliv Rev. 2018. PMID: 29247767 Review.

3

Binding of Small Molecule Drugs to Porcine Vitreous Humor.

Rimpelä AK, Reunanen S, Hagström M, Kidron H, Urtti A. Rimpelä AK, et al. Mol Pharm. 2018 Jun 4;15(6):2174-2179. doi: 10.1021/acs.molpharmaceut.8b00038. Epub 2018 May 4. Mol Pharm. 2018. PMID: 29648838

4

Melanin targeting for intracellular drug delivery: Quantification of bound and free drug in retinal pigment epithelial cells.

Rimpelä AK, Hagström M, Kidron H, Urtti A. Rimpelä AK, et al. J Control Release. 2018 Aug 10;283:261-268. doi: 10.1016/j.jconrel.2018.05.034. Epub 2018 May 31. J Control Release. 2018. PMID: 29859954 Free article.

5

Pharmacokinetic Simulations of Intravitreal Biologicals: Aspects of Drug Delivery to the Posterior and Anterior Segments.

Rimpelä AK, Kiiski I, Deng F, Kidron H, Urtti A. Rimpelä AK, et al. Pharmaceutics. 2018 Dec 30;11(1):9. doi: 10.3390/pharmaceutics11010009. Pharmaceutics. 2018. PMID: 30598037 Free PMC article.

6

Interpretation of Ocular Melanin Drug Binding Assays. Alternatives to the Model of Multiple Classes of Independent Sites.

Manzanares JA, Rimpelä AK, Urtti A. Manzanares JA, et al. Among authors: rimpela ak. Mol Pharm. 2016 Apr 4;13(4):1251-7. doi: 10.1021/acs.molpharmaceut.5b00783. Epub 2016 Feb 5. Mol Pharm. 2016. PMID: 26820602

7

Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs.

Hellinen L, Bahrpeyma S, Rimpelä AK, Hagström M, Reinisalo M, Urtti A. Hellinen L, et al. Among authors: rimpela ak. Pharmaceutics. 2020 Jun 16;12(6):554. doi: 10.3390/pharmaceutics12060554. Pharmaceutics. 2020. PMID: 32560065 Free PMC article.

8

Quantification of Drugs in Distinctly Separated Ocular Substructures of Albino and Pigmented Rats.

Rimpelä AK, Garneau M, Baum-Kroker KS, Schönberger T, Runge F, Sauer A. Rimpelä AK, et al. Pharmaceutics. 2020 Dec 2;12(12):1174. doi: 10.3390/pharmaceutics12121174. Pharmaceutics. 2020. PMID: 33276439 Free PMC article.

9

Mechanistic Model for the Prediction of Small-Molecule Vitreal Clearance Combining Diffusion-Limited and Permeability-Limited Clearance.

Rimpelä AK, Cui Y, Sauer A. Rimpelä AK, et al. Mol Pharm. 2021 Jul 5;18(7):2703-2713. doi: 10.1021/acs.molpharmaceut.1c00236. Epub 2021 Jun 21. Mol Pharm. 2021. PMID: 34151575 Free article.

10

Characterization and Validation of In Vitro and In Vivo Models to Investigate TNF-α-Induced Inflammation in Retinal Diseases.

Weigelt CM, Zippel N, Fuchs H, Rimpelä AK, Schönberger T, Stierstorfer B, Bakker RA, Redemann NH. Weigelt CM, et al. Among authors: rimpela ak. Transl Vis Sci Technol. 2022 May 2;11(5):18. doi: 10.1167/tvst.11.5.18. Transl Vis Sci Technol. 2022. PMID: 35579886 Free PMC article.

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