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Genetic algorithm for the design of molecules with desired properties.
Kamphausen S, Höltge N, Wirsching F, Morys-Wortmann C, Riester D, Goetz R, Thürk M, Schwienhorst A. Kamphausen S, et al. Among authors: riester d. J Comput Aided Mol Des. 2002 Aug-Sep;16(8-9):551-67. doi: 10.1023/a:1021928016359. J Comput Aided Mol Des. 2002. PMID: 12602950
Thrombin inhibitors identified by computer-assisted multiparameter design.
Riester D, Wirsching F, Salinas G, Keller M, Gebinoga M, Kamphausen S, Merkwirth C, Goetz R, Wiesenfeldt M, Stürzebecher J, Bode W, Friedrich R, Thürk M, Schwienhorst A. Riester D, et al. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8597-602. doi: 10.1073/pnas.0501983102. Epub 2005 Jun 3. Proc Natl Acad Sci U S A. 2005. PMID: 15937115 Free PMC article.
Directed evolution towards protease-resistant hirudin variants.
Wirsching F, Keller M, Hildmann C, Riester D, Schwienhorst A. Wirsching F, et al. Among authors: riester d. Mol Genet Metab. 2003 Dec;80(4):451-62. doi: 10.1016/j.ymgme.2003.09.007. Mol Genet Metab. 2003. PMID: 14654359
Fluorogenic assay for penicillin G acylase activity.
Ninkovic M, Riester D, Wirsching F, Dietrich R, Schwienhorst A. Ninkovic M, et al. Among authors: riester d. Anal Biochem. 2001 May 15;292(2):228-33. doi: 10.1006/abio.2001.5078. Anal Biochem. 2001. PMID: 11355855
26 results