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Page 1
Utilization of High-Throughput Experimentation (HTE) and ChemBeads Toward the Development of an Aryl Bromide and Benzyl Bromide Photoredox Cross-Electrophile Coupling.
Org Lett. 2024 Mar 29;26(12):2420-2424. doi: 10.1021/acs.orglett.4c00577. Epub 2024 Mar 18.
Org Lett. 2024.
PMID: 38498905
Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin.
Knight SD, Adams ND, Burgess JL, Chaudhari AM, Darcy MG, Donatelli CA, Luengo JI, Newlander KA, Parrish CA, Ridgers LH, Sarpong MA, Schmidt SJ, Van Aller GS, Carson JD, Diamond MA, Elkins PA, Gardiner CM, Garver E, Gilbert SA, Gontarek RR, Jackson JR, Kershner KL, Luo L, Raha K, Sherk CS, Sung CM, Sutton D, Tummino PJ, Wegrzyn RJ, Auger KR, Dhanak D.
Knight SD, et al. Among authors: ridgers lh.
ACS Med Chem Lett. 2010 Jan 19;1(1):39-43. doi: 10.1021/ml900028r. eCollection 2010 Apr 8.
ACS Med Chem Lett. 2010.
PMID: 24900173
Free PMC article.
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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.
Qian X, McDonald A, Zhou HJ, Adams ND, Parrish CA, Duffy KJ, Fitch DM, Tedesco R, Ashcraft LW, Yao B, Jiang H, Huang JK, Marin MV, Aroyan CE, Wang J, Ahmed S, Burgess JL, Chaudhari AM, Donatelli CA, Darcy MG, Ridgers LH, Newlander KA, Schmidt SJ, Chai D, Colón M, Zimmerman MN, Lad L, Sakowicz R, Schauer S, Belmont L, Baliga R, Pierce DW, Finer JT, Wang Z, Morgan BP, Morgans DJ Jr, Auger KR, Sung CM, Carson JD, Luo L, Hugger ED, Copeland RA, Sutton D, Elliott JD, Jackson JR, Wood KW, Dhanak D, Bergnes G, Knight SD.
Qian X, et al. Among authors: ridgers lh.
ACS Med Chem Lett. 2010 Jan 19;1(1):30-4. doi: 10.1021/ml900018m. eCollection 2010 Apr 8.
ACS Med Chem Lett. 2010.
PMID: 24900171
Free PMC article.
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Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2.
Dhanak D, Christmann LT, Darcy MG, Keenan RM, Knight SD, Lee J, Ridgers LH, Sarau HM, Shah DH, White JR, Zhang L.
Dhanak D, et al. Among authors: ridgers lh.
Bioorg Med Chem Lett. 2001 Jun 4;11(11):1445-50. doi: 10.1016/s0960-894x(01)00249-9.
Bioorg Med Chem Lett. 2001.
PMID: 11378374
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Benzothiopyran-4-one based reversible inhibitors of the human cytomegalovirus (HCMV) protease.
Dhanak D, Keenan RM, Burton G, Kaura A, Darcy MG, Shah DH, Ridgers LH, Breen A, Lavery P, Tew DG, West A.
Dhanak D, et al. Among authors: ridgers lh.
Bioorg Med Chem Lett. 1998 Dec 15;8(24):3677-82. doi: 10.1016/s0960-894x(98)00666-0.
Bioorg Med Chem Lett. 1998.
PMID: 9934494
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Novel ATP-competitive kinesin spindle protein inhibitors.
Parrish CA, Adams ND, Auger KR, Burgess JL, Carson JD, Chaudhari AM, Copeland RA, Diamond MA, Donatelli CA, Duffy KJ, Faucette LF, Finer JT, Huffman WF, Hugger ED, Jackson JR, Knight SD, Luo L, Moore ML, Newlander KA, Ridgers LH, Sakowicz R, Shaw AN, Sung CM, Sutton D, Wood KW, Zhang SY, Zimmerman MN, Dhanak D.
Parrish CA, et al. Among authors: ridgers lh.
J Med Chem. 2007 Oct 4;50(20):4939-52. doi: 10.1021/jm070435y. Epub 2007 Aug 29.
J Med Chem. 2007.
PMID: 17725339
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Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K.
Duffy KJ, Ridgers LH, DesJarlais RL, Tomaszek TA, Bossard MJ, Thompson SK, Keenan RM, Veber DF.
Duffy KJ, et al. Among authors: ridgers lh.
Bioorg Med Chem Lett. 1999 Jul 19;9(14):1907-10. doi: 10.1016/s0960-894x(99)00322-4.
Bioorg Med Chem Lett. 1999.
PMID: 10450951
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