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Editorial: LRRK2-Fifteen Years From Cloning to the Clinic.
Rideout H, Greggio E, Kortholt A, Nichols RJ. Rideout H, et al. Front Neurosci. 2022 Apr 11;16:880914. doi: 10.3389/fnins.2022.880914. eCollection 2022. Front Neurosci. 2022. PMID: 35478845 Free PMC article. No abstract available.
Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.
Helton LG, Soliman A, von Zweydorf F, Kentros M, Manschwetus JT, Hall S, Gilsbach B, Ho FY, Athanasopoulos PS, Singh RK, LeClair TJ, Versées W, Raimondi F, Herberg FW, Gloeckner CJ, Rideout H, Kortholt A, Kennedy EJ. Helton LG, et al. Among authors: rideout h. ACS Chem Biol. 2021 Nov 19;16(11):2326-2338. doi: 10.1021/acschembio.1c00487. Epub 2021 Sep 8. ACS Chem Biol. 2021. PMID: 34496561 Free article.
LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.
Kedariti M, Frattini E, Baden P, Cogo S, Civiero L, Ziviani E, Zilio G, Bertoli F, Aureli M, Kaganovich A, Cookson MR, Stefanis L, Surface M, Deleidi M, Di Fonzo A, Alcalay RN, Rideout H, Greggio E, Plotegher N. Kedariti M, et al. Among authors: rideout h. NPJ Parkinsons Dis. 2022 Jul 19;8(1):92. doi: 10.1038/s41531-022-00354-3. NPJ Parkinsons Dis. 2022. PMID: 35853899 Free PMC article.
Distinct profiles of LRRK2 activation and Rab GTPase phosphorylation in clinical samples from different PD cohorts.
Petropoulou-Vathi L, Simitsi A, Valkimadi PE, Kedariti M, Dimitrakopoulos L, Koros C, Papadimitriou D, Papadimitriou A, Stefanis L, Alcalay RN, Rideout HJ. Petropoulou-Vathi L, et al. Among authors: rideout hj. NPJ Parkinsons Dis. 2022 Jun 8;8(1):73. doi: 10.1038/s41531-022-00336-5. NPJ Parkinsons Dis. 2022. PMID: 35676398 Free PMC article.
Neurobiology of alpha-synuclein.
Vekrellis K, Rideout HJ, Stefanis L. Vekrellis K, et al. Mol Neurobiol. 2004 Aug;30(1):1-21. doi: 10.1385/MN:30:1:001. Mol Neurobiol. 2004. PMID: 15247485 Review.
57 results