Richter W - Search Results

1

Subcutaneous Administration of Biotherapeutics: An Overview of Current Challenges and Opportunities.

Bittner B, Richter W, Schmidt J. Bittner B, et al. Among authors: richter w. BioDrugs. 2018 Oct;32(5):425-440. doi: 10.1007/s40259-018-0295-0. BioDrugs. 2018. PMID: 30043229 Free PMC article. Review.

2

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.

Zheng Y, Tesar DB, Benincosa L, Birnböck H, Boswell CA, Bumbaca D, Cowan KJ, Danilenko DM, Daugherty AL, Fielder PJ, Grimm HP, Joshi A, Justies N, Kolaitis G, Lewin-Koh N, Li J, McVay S, O'Mahony J, Otteneder M, Pantze M, Putnam WS, Qiu ZJ, Ruppel J, Singer T, Stauch O, Theil FP, Visich J, Yang J, Ying Y, Khawli LA, Richter WF. Zheng Y, et al. MAbs. 2012 Mar-Apr;4(2):243-55. doi: 10.4161/mabs.4.2.19387. Epub 2012 Mar 1. MAbs. 2012. PMID: 22453096 Free PMC article.

3

Mechanistic determinants of biotherapeutics absorption following SC administration.

Richter WF, Bhansali SG, Morris ME. Richter WF, et al. AAPS J. 2012 Sep;14(3):559-70. doi: 10.1208/s12248-012-9367-0. Epub 2012 May 23. AAPS J. 2012. PMID: 22619041 Free PMC article. Review.

4

Development of a subcutaneous formulation for trastuzumab - nonclinical and clinical bridging approach to the approved intravenous dosing regimen.

Bittner B, Richter WF, Hourcade-Potelleret F, McIntyre C, Herting F, Zepeda ML, Schmidt J. Bittner B, et al. Among authors: richter wf. Arzneimittelforschung. 2012 Sep;62(9):401-9. doi: 10.1055/s-0032-1321831. Epub 2012 Aug 23. Arzneimittelforschung. 2012. PMID: 22918857 Review.

5

Non-clinical pharmacokinetic/pharmacodynamic and early clinical studies supporting development of a novel subcutaneous formulation for the monoclonal antibody rituximab.

Bittner B, Richter WF, Hourcade-Potelleret F, Herting F, Schmidt J. Bittner B, et al. Among authors: richter wf. Drug Res (Stuttg). 2014 Nov;64(11):569-75. doi: 10.1055/s-0033-1363993. Epub 2014 Jan 22. Drug Res (Stuttg). 2014. PMID: 24452524 Review.

6

Subcutaneous absorption of biotherapeutics: knowns and unknowns.

Richter WF, Jacobsen B. Richter WF, et al. Drug Metab Dispos. 2014 Nov;42(11):1881-9. doi: 10.1124/dmd.114.059238. Epub 2014 Aug 6. Drug Metab Dispos. 2014. PMID: 25100673

7

Non-clinical Safety Evaluation of Biotherapeutics - Challenges, Opportunities and new Insights.

Blaich G, Baumann A, Kronenberg S, de Haan L, Ulrich P, Richter WF, Tibbitts J, Chivers S, Tarcsa E, Caldwell R, Crameri F. Blaich G, et al. Regul Toxicol Pharmacol. 2016 Oct;80S:S1-S14. doi: 10.1016/j.yrtph.2016.08.012. Epub 2016 Aug 27. Regul Toxicol Pharmacol. 2016. PMID: 27578450

8

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing.

Ulrich P, Blaich G, Baumann A, Fagg R, Hey A, Kiessling A, Kronenberg S, Lindecrona RH, Mohl S, Richter WF, Tibbitts J, Crameri F, Weir L. Ulrich P, et al. Regul Toxicol Pharmacol. 2018 Apr;94:91-100. doi: 10.1016/j.yrtph.2018.01.013. Epub 2018 Jan 28. Regul Toxicol Pharmacol. 2018. PMID: 29355662

9

Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice.

Richter WF, Christianson GJ, Frances N, Grimm HP, Proetzel G, Roopenian DC. Richter WF, et al. MAbs. 2018 Jul;10(5):803-813. doi: 10.1080/19420862.2018.1458808. Epub 2018 May 9. MAbs. 2018. PMID: 29621428 Free PMC article.

10

Non-human primates in the PKPD evaluation of biologics: Needs and options to reduce, refine, and replace. A BioSafe White Paper.

Ménochet K, Yu H, Wang B, Tibbitts J, Hsu CP, Kamath AV, Richter WF, Baumann A. Ménochet K, et al. MAbs. 2022 Jan-Dec;14(1):2145997. doi: 10.1080/19420862.2022.2145997. MAbs. 2022. PMID: 36418217 Free PMC article. Review.

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