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Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.
Schuetz DA, de Witte WEA, Wong YC, Knasmueller B, Richter L, Kokh DB, Sadiq SK, Bosma R, Nederpelt I, Heitman LH, Segala E, Amaral M, Guo D, Andres D, Georgi V, Stoddart LA, Hill S, Cooke RM, De Graaf C, Leurs R, Frech M, Wade RC, de Lange ECM, IJzerman AP, Müller-Fahrnow A, Ecker GF. Schuetz DA, et al. Among authors: richter l. Drug Discov Today. 2017 Jun;22(6):896-911. doi: 10.1016/j.drudis.2017.02.002. Epub 2017 Apr 13. Drug Discov Today. 2017. PMID: 28412474 Review.
Medicinal chemistry in the era of big data.
Richter L, Ecker GF. Richter L, et al. Drug Discov Today Technol. 2015 Jul;14:37-41. doi: 10.1016/j.ddtec.2015.06.001. Epub 2015 Jul 14. Drug Discov Today Technol. 2015. PMID: 26194586 Review.
Exploiting open data: a new era in pharmacoinformatics.
Goldmann D, Montanari F, Richter L, Zdrazil B, Ecker GF. Goldmann D, et al. Among authors: richter l. Future Med Chem. 2014 Apr;6(5):503-14. doi: 10.4155/fmc.14.13. Future Med Chem. 2014. PMID: 24649954
The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research.
Ratnam J, Zdrazil B, Digles D, Cuadrado-Rodriguez E, Neefs JM, Tipney H, Siebes R, Waagmeester A, Bradley G, Chau CH, Richter L, Brea J, Evelo CT, Jacoby E, Senger S, Loza MI, Ecker GF, Chichester C. Ratnam J, et al. Among authors: richter l. PLoS One. 2014 Dec 18;9(12):e115460. doi: 10.1371/journal.pone.0115460. eCollection 2014. PLoS One. 2014. PMID: 25522365 Free PMC article.
861 results