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Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.
Moraga I, Wernig G, Wilmes S, Gryshkova V, Richter CP, Hong WJ, Sinha R, Guo F, Fabionar H, Wehrman TS, Krutzik P, Demharter S, Plo I, Weissman IL, Minary P, Majeti R, Constantinescu SN, Piehler J, Garcia KC. Moraga I, et al. Among authors: richter cp. Cell. 2015 Mar 12;160(6):1196-208. doi: 10.1016/j.cell.2015.02.011. Epub 2015 Feb 26. Cell. 2015. PMID: 25728669 Free PMC article.
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations.
Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, Vattulainen I, Hitchcock IS, Piehler J. Wilmes S, et al. Among authors: richter cp. Science. 2020 Feb 7;367(6478):643-652. doi: 10.1126/science.aaw3242. Science. 2020. PMID: 32029621 Free PMC article.
Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane.
Sotolongo Bellón J, Birkholz O, Richter CP, Eull F, Kenneweg H, Wilmes S, Rothbauer U, You C, Walter MR, Kurre R, Piehler J. Sotolongo Bellón J, et al. Among authors: richter cp. Cell Rep Methods. 2022 Feb 4;2(2):100165. doi: 10.1016/j.crmeth.2022.100165. eCollection 2022 Feb 28. Cell Rep Methods. 2022. PMID: 35474965 Free PMC article.
205 results