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Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, Søgaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yıldız-Altay Ü, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE. Tang Q, et al. Among authors: richmond jm. Nat Commun. 2023 Nov 4;14(1):7099. doi: 10.1038/s41467-023-42714-4. Nat Commun. 2023. PMID: 37925520 Free PMC article.
Innate immune mechanisms in vitiligo: danger from within.
Richmond JM, Frisoli ML, Harris JE. Richmond JM, et al. Curr Opin Immunol. 2013 Dec;25(6):676-82. doi: 10.1016/j.coi.2013.10.010. Epub 2013 Nov 12. Curr Opin Immunol. 2013. PMID: 24238922 Free PMC article. Review.
Immunology and skin in health and disease.
Richmond JM, Harris JE. Richmond JM, et al. Cold Spring Harb Perspect Med. 2014 Dec 1;4(12):a015339. doi: 10.1101/cshperspect.a015339. Cold Spring Harb Perspect Med. 2014. PMID: 25452424 Free PMC article. Review.
Simvastatin prevents and reverses depigmentation in a mouse model of vitiligo.
Agarwal P, Rashighi M, Essien KI, Richmond JM, Randall L, Pazoki-Toroudi H, Hunter CA, Harris JE. Agarwal P, et al. Among authors: richmond jm. J Invest Dermatol. 2015 Apr;135(4):1080-1088. doi: 10.1038/jid.2014.529. Epub 2014 Dec 18. J Invest Dermatol. 2015. PMID: 25521459 Free PMC article.
A double-blind, placebo-controlled, phase-II clinical trial to evaluate oral simvastatin as a treatment for vitiligo.
Vanderweil SG, Amano S, Ko WC, Richmond JM, Kelley M, Senna MM, Pearson A, Chowdary S, Hartigan C, Barton B, Harris JE. Vanderweil SG, et al. Among authors: richmond jm. J Am Acad Dermatol. 2017 Jan;76(1):150-151.e3. doi: 10.1016/j.jaad.2016.06.015. J Am Acad Dermatol. 2017. PMID: 27986135 Free PMC article. Clinical Trial. No abstract available.
CXCR3 Depleting Antibodies Prevent and Reverse Vitiligo in Mice.
Richmond JM, Masterjohn E, Chu R, Tedstone J, Youd ME, Harris JE. Richmond JM, et al. J Invest Dermatol. 2017 Apr;137(4):982-985. doi: 10.1016/j.jid.2016.10.048. Epub 2017 Jan 23. J Invest Dermatol. 2017. PMID: 28126463 Free article. No abstract available.
Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo.
Richmond JM, Strassner JP, Zapata L Jr, Garg M, Riding RL, Refat MA, Fan X, Azzolino V, Tovar-Garza A, Tsurushita N, Pandya AG, Tso JY, Harris JE. Richmond JM, et al. Sci Transl Med. 2018 Jul 18;10(450):eaam7710. doi: 10.1126/scitranslmed.aam7710. Sci Transl Med. 2018. PMID: 30021889 Free PMC article.
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