Richardson TG - Search Results

1

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study.

Morales Berstein F, McCartney DL, Lu AT, Tsilidis KK, Bouras E, Haycock P, Burrows K, Phipps AI, Buchanan DD, Cheng I; PRACTICAL consortium; Martin RM, Davey Smith G, Relton CL, Horvath S, Marioni RE, Richardson TG, Richmond RC. Morales Berstein F, et al. Among authors: richardson tg. Elife. 2022 Mar 29;11:e75374. doi: 10.7554/eLife.75374. Elife. 2022. PMID: 35346416 Free PMC article.

2

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants.

Richardson TG, Shihab HA, Hemani G, Zheng J, Hannon E, Mill J, Carnero-Montoro E, Bell JT, Lyttleton O, McArdle WL, Ring SM, Rodriguez S, Campbell C, Smith GD, Relton CL, Timpson NJ, Gaunt TR. Richardson TG, et al. Hum Mol Genet. 2016 Oct 1;25(19):4339-4349. doi: 10.1093/hmg/ddw283. Epub 2016 Aug 24. Hum Mol Genet. 2016. PMID: 27559110 Free PMC article.

3

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

Richardson TG, Zheng J, Davey Smith G, Timpson NJ, Gaunt TR, Relton CL, Hemani G. Richardson TG, et al. Am J Hum Genet. 2017 Oct 5;101(4):590-602. doi: 10.1016/j.ajhg.2017.09.003. Am J Hum Genet. 2017. PMID: 28985495 Free PMC article.

4

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease.

Richardson TG, Haycock PC, Zheng J, Timpson NJ, Gaunt TR, Davey Smith G, Relton CL, Hemani G. Richardson TG, et al. Hum Mol Genet. 2018 Sep 15;27(18):3293-3304. doi: 10.1093/hmg/ddy210. Hum Mol Genet. 2018. PMID: 29893838 Free PMC article.

5

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes.

Ye J, Richardson TG, McArdle WL, Relton CL, Gillespie KM, Suderman M, Hemani G. Ye J, et al. Among authors: richardson tg. J Autoimmun. 2018 Sep;93:66-75. doi: 10.1016/j.jaut.2018.06.005. Epub 2018 Jun 29. J Autoimmun. 2018. PMID: 30146008

6

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics.

Zheng J, Richardson TG, Millard LAC, Hemani G, Elsworth BL, Raistrick CA, Vilhjalmsson B, Neale BM, Haycock PC, Smith GD, Gaunt TR. Zheng J, et al. Among authors: richardson tg. Gigascience. 2018 Aug 1;7(8):giy090. doi: 10.1093/gigascience/giy090. Gigascience. 2018. PMID: 30165448 Free PMC article.

7

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate.

Howe LJ, Richardson TG, Arathimos R, Alvizi L, Passos-Bueno MR, Stanier P, Nohr E, Ludwig KU, Mangold E, Knapp M, Stergiakouli E, Pourcain BS, Smith GD, Sandy J, Relton CL, Lewis SJ, Hemani G, Sharp GC. Howe LJ, et al. Among authors: richardson tg. Epigenomics. 2019 Feb;11(2):133-145. doi: 10.2217/epi-2018-0091. Epub 2019 Jan 14. Epigenomics. 2019. PMID: 30638414 Free PMC article.

8

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization.

Taylor K, Davey Smith G, Relton CL, Gaunt TR, Richardson TG. Taylor K, et al. Among authors: richardson tg. Genome Med. 2019 Jan 31;11(1):6. doi: 10.1186/s13073-019-0613-2. Genome Med. 2019. PMID: 30704512 Free PMC article.

9

Conditioning on a Collider May Induce Spurious Associations: Do the Results of Gale et al. (2017) Support a Health-Protective Effect of Neuroticism in Population Subgroups?

Richardson TG, Davey Smith G, Munafò MR. Richardson TG, et al. Psychol Sci. 2019 Apr;30(4):629-632. doi: 10.1177/0956797618774532. Epub 2019 Feb 22. Psychol Sci. 2019. PMID: 30794476 Free PMC article. No abstract available.

10

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease.

Hatcher C, Relton CL, Gaunt TR, Richardson TG. Hatcher C, et al. Among authors: richardson tg. Transl Psychiatry. 2019 Feb 28;9(1):105. doi: 10.1038/s41398-019-0437-2. Transl Psychiatry. 2019. PMID: 30820025 Free PMC article.

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