Richardson TG - Search Results

1

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.

Yarmolinsky J, Díez-Obrero V, Richardson TG, Pigeyre M, Sjaarda J, Paré G, Walker VM, Vincent EE, Tan VY, Obón-Santacana M, Albanes D, Hampe J, Gsur A, Hampel H, Pai RK, Jenkins M, Gallinger S, Casey G, Zheng W, Amos CI; International Lung Cancer Consortium; PRACTICAL consortium; MEGASTROKE consortium; Smith GD, Martin RM, Moreno V. Yarmolinsky J, et al. Among authors: richardson tg. PLoS Med. 2022 Feb 3;19(2):e1003897. doi: 10.1371/journal.pmed.1003897. eCollection 2022 Feb. PLoS Med. 2022. PMID: 35113855 Free PMC article.

2

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants.

Richardson TG, Shihab HA, Hemani G, Zheng J, Hannon E, Mill J, Carnero-Montoro E, Bell JT, Lyttleton O, McArdle WL, Ring SM, Rodriguez S, Campbell C, Smith GD, Relton CL, Timpson NJ, Gaunt TR. Richardson TG, et al. Hum Mol Genet. 2016 Oct 1;25(19):4339-4349. doi: 10.1093/hmg/ddw283. Epub 2016 Aug 24. Hum Mol Genet. 2016. PMID: 27559110 Free PMC article.

3

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

Richardson TG, Zheng J, Davey Smith G, Timpson NJ, Gaunt TR, Relton CL, Hemani G. Richardson TG, et al. Am J Hum Genet. 2017 Oct 5;101(4):590-602. doi: 10.1016/j.ajhg.2017.09.003. Am J Hum Genet. 2017. PMID: 28985495 Free PMC article.

4

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease.

Richardson TG, Haycock PC, Zheng J, Timpson NJ, Gaunt TR, Davey Smith G, Relton CL, Hemani G. Richardson TG, et al. Hum Mol Genet. 2018 Sep 15;27(18):3293-3304. doi: 10.1093/hmg/ddy210. Hum Mol Genet. 2018. PMID: 29893838 Free PMC article.

5

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics.

Zheng J, Richardson TG, Millard LAC, Hemani G, Elsworth BL, Raistrick CA, Vilhjalmsson B, Neale BM, Haycock PC, Smith GD, Gaunt TR. Zheng J, et al. Among authors: richardson tg. Gigascience. 2018 Aug 1;7(8):giy090. doi: 10.1093/gigascience/giy090. Gigascience. 2018. PMID: 30165448 Free PMC article.

6

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization.

Taylor K, Davey Smith G, Relton CL, Gaunt TR, Richardson TG. Taylor K, et al. Among authors: richardson tg. Genome Med. 2019 Jan 31;11(1):6. doi: 10.1186/s13073-019-0613-2. Genome Med. 2019. PMID: 30704512 Free PMC article.

7

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.

Treur JL, Demontis D, Smith GD, Sallis H, Richardson TG, Wiers RW, Børglum AD, Verweij KJH, Munafò MR. Treur JL, et al. Among authors: richardson tg. Addict Biol. 2021 Jan;26(1):e12849. doi: 10.1111/adb.12849. Epub 2019 Nov 16. Addict Biol. 2021. PMID: 31733098 Free PMC article.

8

The Effect of Plasma Lipids and Lipid-Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study.

Zheng J, Brion MJ, Kemp JP, Warrington NM, Borges MC, Hemani G, Richardson TG, Rasheed H, Qiao Z, Haycock P, Ala-Korpela M, Davey Smith G, Tobias JH, Evans DM. Zheng J, et al. Among authors: richardson tg. J Bone Miner Res. 2020 Jul;35(7):1224-1235. doi: 10.1002/jbmr.3989. Epub 2020 Mar 12. J Bone Miner Res. 2020. PMID: 32163637 Free article.

9

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.

Richardson TG, Sanderson E, Palmer TM, Ala-Korpela M, Ference BA, Davey Smith G, Holmes MV. Richardson TG, et al. PLoS Med. 2020 Mar 23;17(3):e1003062. doi: 10.1371/journal.pmed.1003062. eCollection 2020 Mar. PLoS Med. 2020. PMID: 32203549 Free PMC article.

10

Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study.

Richardson TG, Sanderson E, Elsworth B, Tilling K, Davey Smith G. Richardson TG, et al. BMJ. 2020 May 6;369:m1203. doi: 10.1136/bmj.m1203. BMJ. 2020. PMID: 32376654 Free PMC article.

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