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Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice.
Pak HH, Haws SA, Green CL, Koller M, Lavarias MT, Richardson NE, Yang SE, Dumas SN, Sonsalla M, Bray L, Johnson M, Barnes S, Darley-Usmar V, Zhang J, Yen CE, Denu JM, Lamming DW. Pak HH, et al. Among authors: richardson ne. Nat Metab. 2021 Oct;3(10):1327-1341. doi: 10.1038/s42255-021-00466-9. Epub 2021 Oct 18. Nat Metab. 2021. PMID: 34663973 Free PMC article.
Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice.
Richardson NE, Konon EN, Schuster HS, Mitchell AT, Boyle C, Rodgers AC, Finke M, Haider LR, Yu D, Flores V, Pak HH, Ahmad S, Ahmed S, Radcliff A, Wu J, Williams EM, Abdi L, Sherman DS, Hacker T, Lamming DW. Richardson NE, et al. Nat Aging. 2021 Jan;1(1):73-86. doi: 10.1038/s43587-020-00006-2. Epub 2021 Jan 14. Nat Aging. 2021. PMID: 33796866 Free PMC article.
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, Jang C, Kasza I, Nikodemova M, Wakai MH, Tomasiewicz JL, Yang SE, Miller BR, Pak HH, Brinkman JA, Rojas JM, Quinn WJ 3rd, Cheng EP, Konon EN, Haider LR, Finke M, Sonsalla M, Alexander CM, Rabinowitz JD, Baur JA, Malecki KC, Lamming DW. Yu D, et al. Among authors: richardson ne. Cell Metab. 2021 May 4;33(5):905-922.e6. doi: 10.1016/j.cmet.2021.03.025. Epub 2021 Apr 21. Cell Metab. 2021. PMID: 33887198 Free PMC article.
Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction.
Green CL, Pak HH, Richardson NE, Flores V, Yu D, Tomasiewicz JL, Dumas SN, Kredell K, Fan JW, Kirsh C, Chaiyakul K, Murphy ME, Babygirija R, Barrett-Wilt GA, Rabinowitz J, Ong IM, Jang C, Simcox J, Lamming DW. Green CL, et al. Among authors: richardson ne. Cell Metab. 2022 Feb 1;34(2):209-226.e5. doi: 10.1016/j.cmet.2021.12.018. Cell Metab. 2022. PMID: 35108511 Free PMC article.
Regulation of metabolic health by dietary histidine in mice.
Flores V, Spicer AB, Sonsalla MM, Richardson NE, Yu D, Sheridan GE, Trautman ME, Babygirija R, Cheng EP, Rojas JM, Yang SE, Wakai MH, Hubbell R, Kasza I, Tomasiewicz JL, Green CL, Dantoin C, Alexander CM, Baur JA, Malecki KC, Lamming DW. Flores V, et al. Among authors: richardson ne. J Physiol. 2023 Jun;601(11):2139-2163. doi: 10.1113/JP283261. Epub 2022 Sep 27. J Physiol. 2023. PMID: 36086823
[No title available]
[No authors listed] [No authors listed] PMID: 35109090
Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E2 Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes.
Schaid MD, Zhu Y, Richardson NE, Patibandla C, Ong IM, Fenske RJ, Neuman JC, Guthery E, Reuter A, Sandhu HK, Fuller MH, Cox ED, Davis DB, Layden BT, Brasier AR, Lamming DW, Ge Y, Kimple ME. Schaid MD, et al. Among authors: richardson ne. Metabolites. 2021 Jan 16;11(1):58. doi: 10.3390/metabo11010058. Metabolites. 2021. PMID: 33467110 Free PMC article.
59 results