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Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.
Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, Gaffen SL. Verma AH, et al. Among authors: richardson jp. Sci Immunol. 2017 Nov 3;2(17):eaam8834. doi: 10.1126/sciimmunol.aam8834. Sci Immunol. 2017. PMID: 29101209 Free PMC article.
Candida albicans pathogenicity and epithelial immunity.
Naglik JR, Richardson JP, Moyes DL. Naglik JR, et al. Among authors: richardson jp. PLoS Pathog. 2014 Aug 14;10(8):e1004257. doi: 10.1371/journal.ppat.1004257. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25121985 Free PMC article. Review. No abstract available.
Candidalysin is a fungal peptide toxin critical for mucosal infection.
Moyes DL, Wilson D, Richardson JP, Mogavero S, Tang SX, Wernecke J, Höfs S, Gratacap RL, Robbins J, Runglall M, Murciano C, Blagojevic M, Thavaraj S, Förster TM, Hebecker B, Kasper L, Vizcay G, Iancu SI, Kichik N, Häder A, Kurzai O, Luo T, Krüger T, Kniemeyer O, Cota E, Bader O, Wheeler RT, Gutsmann T, Hube B, Naglik JR. Moyes DL, et al. Among authors: richardson jp. Nature. 2016 Apr 7;532(7597):64-8. doi: 10.1038/nature17625. Epub 2016 Mar 30. Nature. 2016. PMID: 27027296 Free PMC article.
IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.
Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL. Conti HR, et al. Among authors: richardson jp. Cell Host Microbe. 2016 Nov 9;20(5):606-617. doi: 10.1016/j.chom.2016.10.001. Epub 2016 Oct 27. Cell Host Microbe. 2016. PMID: 27923704 Free PMC article.
239 results