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The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma.
Newton GK, Perrior TR, Jenkins K, Major MR, Key RE, Stewart MR, Firth-Clark S, Lloyd SM, Zhang J, Francis-Newton NJ, Richardson JP, Chen J, Lai P, Garrod DR, Robinson C. Newton GK, et al. Among authors: richardson jp. J Med Chem. 2014 Nov 26;57(22):9447-62. doi: 10.1021/jm501102h. Epub 2014 Nov 17. J Med Chem. 2014. PMID: 25365789 Free PMC article.
Targeting an Initiator Allergen Provides Durable and Expansive Protection against House Dust Mite Allergy.
Zhang J, Chen J, Richardson JP, Francis-Newton NJ, Lai PF, Jenkins K, Major MR, Key RE, Stewart ME, Firth-Clark S, Lloyd SM, Newton GK, Perrior TR, Garrod DR, Robinson C. Zhang J, et al. Among authors: richardson jp. ACS Pharmacol Transl Sci. 2022 Aug 12;5(9):735-751. doi: 10.1021/acsptsci.2c00022. eCollection 2022 Sep 9. ACS Pharmacol Transl Sci. 2022. PMID: 36110379 Free PMC article.
Candida albicans pathogenicity and epithelial immunity.
Naglik JR, Richardson JP, Moyes DL. Naglik JR, et al. Among authors: richardson jp. PLoS Pathog. 2014 Aug 14;10(8):e1004257. doi: 10.1371/journal.ppat.1004257. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25121985 Free PMC article. Review. No abstract available.
Some like it hot: Candida activation of inflammasomes.
Camilli G, Griffiths JS, Ho J, Richardson JP, Naglik JR. Camilli G, et al. Among authors: richardson jp. PLoS Pathog. 2020 Oct 29;16(10):e1008975. doi: 10.1371/journal.ppat.1008975. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33119702 Free PMC article. No abstract available.
Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences.
Müller R, König A, Groth S, Zarnowski R, Visser C, Handrianz T, Maufrais C, Krüger T, Himmel M, Lee S, Priest EL, Yildirim D, Richardson JP, Blango MG, Bougnoux ME, Kniemeyer O, d'Enfert C, Brakhage AA, Andes DR, Trümper V, Nehls C, Kasper L, Mogavero S, Gutsmann T, Naglik JR, Allert S, Hube B. Müller R, et al. Among authors: richardson jp. Nat Microbiol. 2024 Mar;9(3):669-683. doi: 10.1038/s41564-024-01606-z. Epub 2024 Feb 22. Nat Microbiol. 2024. PMID: 38388771
Different viral genes modulate virulence in model mammal hosts and Culex pipiens vector competence in Mediterranean basin lineage 1 West Nile virus strains.
Fiacre L, Nougairède A, Migné C, Bayet M, Cochin M, Dumarest M, Helle T, Exbrayat A, Pagès N, Vitour D, Richardson JP, Failloux AB, Vazeille M, Albina E, Lecollinet S, Gonzalez G. Fiacre L, et al. Among authors: richardson jp. Front Microbiol. 2024 Jan 17;14:1324069. doi: 10.3389/fmicb.2023.1324069. eCollection 2023. Front Microbiol. 2024. PMID: 38298539 Free PMC article.
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis.
Wu Y, Du S, Bimler LH, Mauk KE, Lortal L, Kichik N, Griffiths JS, Osicka R, Song L, Polsky K, Kasper L, Sebo P, Weatherhead J, Knight JM, Kheradmand F, Zheng H, Richardson JP, Hube B, Naglik JR, Corry DB. Wu Y, et al. Among authors: richardson jp. Cell Rep. 2023 Oct 31;42(10):113240. doi: 10.1016/j.celrep.2023.113240. Epub 2023 Oct 17. Cell Rep. 2023. PMID: 37819761 Free PMC article.
Host Genotype Links to Salivary and Gut Microbiota by Periodontal Status.
Kurushima Y, Wells PM, Bowyer RCE, Zoheir N, Doran S, Richardson JP, Sprockett DD, Relman DA, Steves CJ, Nibali L. Kurushima Y, et al. Among authors: richardson jp. J Dent Res. 2023 Feb;102(2):146-156. doi: 10.1177/00220345221125402. Epub 2022 Oct 8. J Dent Res. 2023. PMID: 36214094 Free PMC article.
239 results