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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 2
2004 2
2005 3
2006 5
2007 6
2008 6
2009 5
2010 6
2011 7
2012 9
2013 5
2014 7
2015 12
2016 12
2017 19
2018 24
2019 21
2020 12
2021 19
2022 5
2023 8
2024 7

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177 results

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Page 1
JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Fortelny N, Farlik M, Fife V, Gorki AD, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Ravi Sundar Jose Geetha A, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T, Müller M, Bock C. Fortelny N, et al. Among authors: moriggl r. Nat Immunol. 2024 Apr 24. doi: 10.1038/s41590-024-01804-1. Online ahead of print. Nat Immunol. 2024. PMID: 38658806
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.
Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman MW, Eder T, Abdallah DI, Maurer B, Wagner C, Schönefeldt S, Spirk K, Pichler A, Pemovska T, Schweicker C, Pölöske D, Hubanic E, Jungherz D, Müller TA, Aung MMK, Orlova A, Pham HTT, Zimmel K, Krausgruber T, Bock C, Müller M, Dahlhoff M, Boersma A, Rülicke T, Fleck R, de Araujo ED, Gunning PT, Aittokallio T, Mustjoki S, Sanda T, Hartmann S, Grebien F, Hoermann G, Haferlach T, Staber PB, Neubauer HA, Look AT, Herling M, Moriggl R. Suske T, et al. Among authors: moriggl r. J Clin Invest. 2024 Apr 15;134(8):e168536. doi: 10.1172/JCI168536. J Clin Invest. 2024. PMID: 38618957 Free PMC article.
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Randhawa M, Trifinopoulos J, Maurer B, Grausenburger R, Bertram CA, Moriggl RH, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D. Klein K, et al. Among authors: moriggl rh. Blood. 2024 Mar 18:blood.2023022655. doi: 10.1182/blood.2023022655. Online ahead of print. Blood. 2024. PMID: 38498036 Free article.
Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.
Minas TZ, Han J, Javaheri T, Hong SH, Schlederer M, Saygideğer-Kont Y, Çelik H, Mueller KM, Temel I, Özdemirli M, Kovar H, Erkizan HV, Toretsky J, Kenner L, Moriggl R, Üren A. Minas TZ, et al. Among authors: moriggl r. Oncotarget. 2024 Feb 22;15:143. doi: 10.18632/oncotarget.28524. Oncotarget. 2024. PMID: 38386842 Free PMC article. No abstract available.
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors.
Keeley AB, Kopranovic A, Di Lorenzo V, Ábrányi-Balogh P, Jänsch N, Lai LN, Petri L, Orgován Z, Pölöske D, Orlova A, Németh AG, Desczyk C, Imre T, Bajusz D, Moriggl R, Meyer-Almes FJ, Keserü GM. Keeley AB, et al. Among authors: moriggl r. J Med Chem. 2024 Jan 11;67(1):572-585. doi: 10.1021/acs.jmedchem.3c01779. Epub 2023 Dec 19. J Med Chem. 2024. PMID: 38113354 Free PMC article.
Medicinal chemistry advances in targeting class I histone deacetylases.
Abdallah DI, de Araujo ED, Patel NH, Hasan LS, Moriggl R, Krämer OH, Gunning PT. Abdallah DI, et al. Among authors: moriggl r. Explor Target Antitumor Ther. 2023;4(4):757-779. doi: 10.37349/etat.2023.00166. Epub 2023 Aug 31. Explor Target Antitumor Ther. 2023. PMID: 37711592 Free PMC article. Review.
177 results